Common Comparisons Flashcards
location of ARTERIAL ULCERS vs VENOUS ULCERS?
Arterial:
Tips of toes, lateral malleolus
Venous:
Gaiter area
appearance of ARTERIAL ULCERS?
punched-out
pale tissue
minimally exudative
appearance of VENOUS ULCERS?
irregular shape
firm oedema
moderately-highly exudative
ISCHAEMIC COLITIS vs MESENTERIC ISCHAEMIA:
patho?
Ischaemic colitis:
Restricted blood flow to LI
Mesenteric ischaemia:
Restricted blood flow to SI
ISCHAEMIC COLITIS vs MESENTERIC ISCHAEMIA:
most common cause?
Ischaemic colitis:
IMA thrombosis
Mesenteric ischaemia:
SMA thrombosis
ISCHAEMIC COLITIS vs MESENTERIC ISCHAEMIA:
Sx?
Ischaemic colitis:
low left abdo pain
Mesenteric ischaemia:
central/RIF abdo pain
ISCHAEMIC COLITIS vs MESENTERIC ISCHAEMIA:
Gold Ix?
Ischaemic colitis:
colonoscopy + biopsy
Mesenteric ischaemia:
CT w/ contrast
ISCHAEMIC COLITIS vs MESENTERIC ISCHAEMIA:
Tx?
Both:
IV fluids + Abx, Heparin
RA vs OA:
Age of onset?
RA:
Any age
OA:
Later in life
RA vs OA:
Speed of onset
RA:
Rapid (weeks-months)
OA:
Slow (years)
RA vs OA:
Distribution?
RA:
Symmetrical polyarthritis
OA:
Asymmetrical monoarthritis (–> poly)
RA vs OA:
Joints affected?
RA:
Small joints of hands + feet (MCP + PIP)
OA:
Weight-bearing joints (knee, hip, base of thumb, big toe)
RA vs OA:
Are DIP joints spared?
RA:
YES - DIP spared
OA:
NO - DIP affected
RA vs OA:
Duration of morning stiffness?
RA:
>30 mins
OA:
<30 mins
RA vs OA:
When is stiffness worst (am/pm)?
RA:
am
OA:
pm
RA vs OA:
Effect of movement?
RA:
pain eases
OA:
pain worsens
RA vs OA:
Any systemic Sx?
RA:
Yes (fatigue, fever, night sweats)
OA:
No
GOUT vs PSEUDOGOUT:
Crystals?
Gout:
Monosodium urate crystals
Pseudogout:
Calcium pyrophosphate crystals
GOUT vs PSEUDOGOUT:
Serum uric acid levels?
Gout:
Raised
Pseudogout:
Normal
GOUT vs PSEUDOGOUT:
Joints affected?
Gout:
Small joints (esp. big toe)
Pseudogout:
Large joints (esp. knee)
GOUT vs PSEUDOGOUT:
Pain severity?
Gout:
Severe
Pseudogout:
Moderate
GOUT vs PSEUDOGOUT:
Common age + gender?
Gout:
<40 yrs men
Pseudogout:
Elderly women
NEPHROTIC vs NEPHRITIC:
Severity of proteinuria?
Nephrotic:
Severe (“o” in “nephrotic” means “lots” of protein)
Nephritic:
Mild
NEPHROTIC vs NEPHRITIC:
Which has hypoalbuminemia?
Nephrotic
NEPHROTIC vs NEPHRITIC:
Which has peripheral oedema?
Nephrotic
NEPHROTIC vs NEPHRITIC:
Which has hyperlipidaemia?
Nephrotic
NEPHROTIC vs NEPHRITIC:
Which has oliguria?
nephritic
NEPHROTIC vs NEPHRITIC:
Which has haematuria (“coca-cola urine”)?
nephritic
NEPHROTIC vs NEPHRITIC:
Which has HTN?
nephritic
IgA nephropathy (/Berger’s) - nephritic or nephrotic?
nephritic
Post-strep glomerulonephritis- nephritic or nephrotic?
nephritic
Goodpasture’s syndrome - nephritic or nephrotic?
nephritic
SLE neuropathy - nephritic or nephrotic?
nephritic
Minimal change disease - nephritic or nephrotic?
nephrotic
Focal segmental glomerulosclerosis - nephritic or nephrotic?
nephrotic
Membranous nephropathy - nephritic or nephrotic?
nephrotic
TYPE 1 vs TYPE 2 resp failure:
pO2 + pCO2?
Type 1:
low pO2, low/normal pCO2
Type 2:
low pO2, high pCO2
TYPE 1 vs TYPE 2 resp failure:
Most common cause?
Type 1:
PE
Type 2:
Hypoventilation
TYPE 1 vs TYPE 2 resp failure:
Examples?
Type 1:
PE, ILD (fibrosing alveolitis, sarcoidosis)
Type 2:
Hypoventilation, asthma, COPD, bronchiectasis, pneumonia
TYPE 1 vs TYPE 2 resp failure:
Restrictive or obstructive?
Type 1:
Restrictive
(V/Q mismatch so O2 struggles to cross the alveolar wall into blood but CO2 is more soluble so can cross)
Type 2:
Obstructive
(both O2 + CO2 struggle to get in + out of alveoli, maybe due to alvolar wall thickening)
TYPE 1 vs TYPE 2 resp failure:
FEV1/FVC?
Type 1:
FEV1/FVC >0.7
Type 2:
FEV1/FVC <0.7
TYPE 1 vs TYPE 2 resp failure:
FVC + FEV1?
Type 1:
FVC + FEV1 <80% PV
Type 2:
FEV1 lower than FVC
TYPE 1 vs TYPE 2 resp failure:
Tx?
Type 1:
Needs O2
Type 2:
Needs help with breathing (e.g. mechanical ventilation)
TYPE 1 vs TYPE 2 resp failure:
Signs + Sx?
Type 1:
Small lung volume
Most of breath out in first second
Type 2:
Bounding pulse
Flapping tremor
Confusion
Reduced GCS
UC vs Crohn’s:
How deep is the inflammation?
UC:
Mucosal only
Crohn’s:
Transmural
UC vs Crohn’s:
What part of the gut is affected?
UC:
Never affects proximal to the ilocaecal valve
Crohn’s:
Any part of gut
UC vs Crohn’s:
Is inflammation continuous or not?
UC:
Continuous
Crohn’s:
Skip lesions
UC vs Crohn’s:
Which has a cobblestone appearance?
Crohn’s
UC vs Crohn’s:
Which has lots of granulomas?
Crohn’s
UC vs Crohn’s:
Which has more crypt abscesses?
UC
UC vs Crohn’s:
Give 2 extra-intestinal signs
Clubbing, oral aphthous ulcers
UC vs Crohn’s:
Where is the pain?
UC:
LLQ pain
Crohn’s:
RIF pain
UC vs Crohn’s:
pANCA?
UC:
+ve pANCA
Crohn’s:
-ve pANCA
UC vs Crohn’s:
Which has depleted goblet cells?
UC
UC vs Crohn’s:
Effect of smoking?
UC:
Protective
(so is appendicectomy)
Crohn’s:
Exacerbates Sx
UC vs Crohn’s:
Any complications?
UC:
PSC (primary sclerosing cholangitis)
UC vs Crohn’s:
Tx if mild?
UC:
5-ASA (e.g. Mesalazine)
Crohn’s:
Prednisolone
UC vs Crohn’s:
Tx if severe?
UC:
Prednisolone
Crohn’s:
IV/rectal hydrocortisone +/- Abx
UC vs Crohn’s:
Tx to maintain remission?
Azathioprine
IgA nephropathy vs post-strep glomerulonephritis?
IgA nephropathy:
Illness DAYS before
Post-strep glomerulonephritis:
Resp illness 2-3 WEEKS before