Side Effects Flashcards

0
Q

2 side effects of cholestyramine (questran)

A

Constipation

Decreased absorption of fat soluble vitamins

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1
Q

3 side effects of lovastatin (mevacor)

A

Headache
Rash
Hepatotoxicity (rare)

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2
Q

Side effects of Nicotinic acid (7)

A
Flushing
Itching
Nausea
Vomiting
Gastric upset
Hepatotoxicity
Hyperglycemia
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3
Q

4 side effects of gemfibrozil (lopid)

A

Rashes
Gastrointestinal
Gallstones
Hepatotoxicity

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4
Q

3 side effects of fludrocortisone (Florinef) treats Addison’s disease, primary hypoaldosteronism, congenital adrenal hyperplasia

A

Hypertension
Hypokalemia
Edema

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5
Q

Drugs to treat diabetes insipidus all end with

A

Pressin (vasopressin, desmopressin, lypressin)

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6
Q

Adverse effects of PRESSIN drugs

A

Water intoxication

Vasoconstriction

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7
Q

Adverse effects of octreotide (sandostatin) 2 -suppresses growth hormone release

A

Gastrointestinal

Gallstones

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8
Q

Somatrem (protropin) 4 adverse effects and treats dwarfism

A

Hyperglycemia
Hypothyroidism
Antibody formation
Poverty (treatment can be $25 k/yr)

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9
Q

Acromegaly is

A

Growth hormone excess

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10
Q

Propylthiouracil adverse effects

A

Agranulocytosis (within first 2 mos)
Hypothyroidism (w excessive dosing)
Neonatal hypothyroidism

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11
Q

Levothyroxine has 3 adverse effects

A

Tachycardia
Angina
Tremors

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12
Q

Sulfonylureas (orinase) promotes

A

Insulin secretion

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13
Q

Metformin (glucophage)

A

Decreases glucose production by liver and increase glucose uptake by muscle and decreases insulin resistance

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14
Q

Acarbose

A

Decreases rise in blood glucose

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15
Q

Troglitazone

A

Decreases insulin resistance increases glucose uptake by muscle and decreases glucose production by liver

16
Q

Oprelvekin (neumega) has what two adverse effects

A

Fluid retention

Cardiac dysrhythmias

17
Q

Sargramostim has what adverse effect

A

Bone pain

18
Q

Filgrastim has what adverse effect

A

Bone pain

19
Q

Epoetin Alfa (epogen) adverse effect

A

Hypertension

20
Q

Cyanocobalamin adverse effect

A

Hypokalemia

21
Q

Luteinizing hormone

A

Acts in women to promote ovulation and in men to promote androgen production

22
Q

Drugs that act at the brain stem

A

Clonidine

Methyldopa

23
Q

Drug that acts at the sympathetic ganglia

A

Mecamylamine

24
Q

Drugs that act on vascular smooth muscle -6

A
Hydralazine 
Minoxidil
Nitroprusside
Diazoxide
Ca channel blockers
Thiazides
25
Q

Drugs that act at vascular alpha receptors -3

A

Prazosin
Terazosin
Lebetalol

26
Q

Drugs that act at adrenergic terminals -2

A

Guanethidine

Reserpine

27
Q

Drugs that act at renal tubules

A

Thiazide diuretics
Furosemide
Potassium sparing diuretics

28
Q

Drugs that act at beta receptors on juxtaglomerular cells -3

A

Propranolol
Metoprolol
Other beta blockers

29
Q

Drugs that act at ACE

A

Captopril
Enalapril
Lisinopril
Other prils

30
Q

Drugs that act at angiotensin II receptors

A

Losartan
Valsartan
Other ARBS

31
Q

Drugs that act at aldosterone receptors -2

A

Eplerenone

Spironolactone