Ch 44 Flashcards

0
Q

Calcium channels are always coupled with what other receptors?

A

Beta 1 adrenergic receptors

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1
Q

Calcium channels help regulate functions of what 3 areas

A

Myocardium
SA node
AV node

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2
Q

Calcium channel blockers / calcium antagonist prevent calcium ions from doing what

A

Entering cells therefor preventing contraction

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3
Q

CCBs and beta blockers have the same action on heart and that’s what

A

Reduce force of contraction and slow heart rate

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4
Q

What are three classes of CCBs

A

Nifedipine
Verapamil
Diltiazem

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5
Q

Nifedipine (adalat) - CCB blocks calcium in blood vessels (arterioles only) causing vasodilation. The three major indications are what

A

Angina pectoris
Hypertension
Migraine headaches

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6
Q

Verapamil (calan) - CCB blocks calcium in blood vessels and heart. Three major indications are what

A

Angina pectoris
Essential hypertension
Cardiac dysthymias

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7
Q

What are 7 adverse effects of verapramil (CCB)

A
Constipation 
Dizziness
Facial flushing 
Headache 
Edema of ankles 
Gingival hyperplasia (overgrowth of gum tissue) 
Heart block
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8
Q

CCBs should be used with GREAT CAUTION because of increased risk of mortality in patients with what 3 disorders

A

Myocardial infarction
Unstable angina
Hypertension

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