Shock I Flashcards

1
Q

shock

A

arterial blood flow inadequate to meet tissue O2 demand

defined by CO, preload, and afterload

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2
Q

shock defined by

A

CO, preload, and afterload

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3
Q

pulmonary capillary wedge pressure

A

PCWP

-left atrial pressure

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4
Q

hypovolemic shock

A

decreased CO
decreased PCWP
increased SVR

hemorrhage, fluid loss, poor intake

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5
Q

systemic vascular resistance

A

SVR

afterload indicator

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6
Q

cardiogenic shock

A

decreased CO
increased PCWP
increased SVR

cardiomyopathy, arrhythmia, mechanical, obstruction (tamponade, PE, tension pneumo)

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7
Q

distributive shock

A

vasodilatory - warm

increased CO
decreased SVR
decreased PCWP

sepsis, TSS, anaphylaxis, toxin, spinal cord injury

normal to high central venous O2 sat

blood to skin

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8
Q

SBP < 90

A

marker for shock

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9
Q

markers for shock

A
  1. SBP < 90
  2. 3 windows - cutaneous - mottled, renal < 0.5, neuro - abnormal mentation
  3. blood lactate > 1
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10
Q

levito reticualris

A

giraffe looking skin

in shock

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11
Q

alcoholic, cirrhosis, ascites, vomiting, dry membranes, BP 70/50

A

hypovolemic shock

will see

  • decreased CO
  • decreased PCWP
  • decreased CVP
  • increased SVR
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12
Q

CVP

A

right atrial pressure

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13
Q

Tx of hypovolemic shock

A

0.9% saline - 1-2 liters wide open - continue based on BP, skin, urine, and mental status

PRBCs

goal - CVP 8-12mmHg

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14
Q

dobutamine

A

inotropic

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15
Q

dyspnea, BP 65/50, old MI, HR 140, cool skin, clammy skin, restless, basilar crackles, distended neck veins

A

cardiogenic shock

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16
Q

Tx of cardiogenic shock

A
O2
dobutamine (low BP)
nitro (normal/high BP)
AF
post MI - NE, dopamine, milrinone
17
Q

NE

A

vasopressor with some inotropic

18
Q

dopamine

A

alpha agonist with some inotropic

-increases PCWP

19
Q

milrinone

A

inotrope that also produce vasodilation

Tx for cardiogenic shock - if patient does not have that severe hypotension

20
Q

becks triad

A

for cardiac tamponade

1 - distended neck veins
2 - muffled heart sounds
3 - hypotension

21
Q

echocardiography with free space around ventricular wall

A

obstructive shock

22
Q

obstructive shock

A
tension pneumo
pericardial disease
PE
cardiac tumor
left atrial mural thrombus
obstructive valvular disease
23
Q

SIRS

A

systemic immune response syndrome
-dysregulated inflammation related to autoimmune, pancreatitis, vasculitis, VTE, burns, surgery, etc.

usually respiratory alkalosis

24
Q

respiratory alkalosis

A

with SIRS

25
Q

labs in SIRS, sepsis, distributive shock

A
CMP
ABG
type and crossmatch
coag parameters
lactate 
blood culture
26
Q

clustered gram positive cocci

A

staph

27
Q

DAMPs

A

damage-associated molecular patterns

activate TLRs

28
Q

PAMPs

A

pathogen-associated molecular patterns

activate TLRs

29
Q

SIRS

A

TPR

  • temp >38.3
  • pulse > 90
  • respirations > 20

with infection - becomes sepsis

30
Q

WBC > 12,000 with bandemia >10%

A

sepsis

31
Q

WBC < 4,000 with increased CRP and procalcitonin

A

sepsis

32
Q

variables with sepsis

A

inflammatory
-WBC levels high, or elevated CRP and procalcitonin

hemodynamic
-SBP < 90, MAP < 70

organic dysfunction
-PaO2 0.5
INR >1.5
ileus
platelets < 100,000
bilirubin >4
hyperprolactinemia
decreased cap refill
33
Q

severe sepsis

A

involves at least ONE organ system

ARDS, AFR, DIC, serum lactate >4

34
Q

unable to maintain MAP >60 after fluid resuscitation

A

septic shock

35
Q

distributive shock

A

septic shock, anaphylaxis, adrenal insufficiency

SVR <800***

and elevated mixed venous O2 sat**

36
Q

sepsis protocol

A

within 2 hours pt with infection, SIRS, dysfunction of one organ

1 - serum lactate
2 - 2x blood cultures
3 - 2 18 gauge lines
4 - antibiotics
5 - 2L normal saline
6 - CBC and BMP
7 - O2 sat >90
8 - NE if shock present
9 - transfer - lactate >4, SBP <60 after 2 L normal saline
37
Q

goal for septic shock

A

maintain CVP 8-12
fluids - 5L in 6 hrs
maintain MAP >65
cardiac index 2-4

NE - vasopressor
phenylephrine - warm shock
E - anaphylactic shock
vasopressin - potentiates NE

maintain CV O2 sat - >70
PRBCs

dobutamine

goal - reduce lactate by 20% in first 2 hours

38
Q

relative adrenal insufficiency

A

use hydrocortisone 50mg q6hrs