Ischemic Heart Disease, Angina, and MI I Flashcards
coronary blood demand exceeds coronary blood flow
ischemic heart disease
etiology of IHD
atherosclerosis hyperthyroid anemia stress variant angina
prinzmetal
vasospasm
retrosternal, aching or squeezing, radiates to neck, shoulder, back, teeth, and epigastrium
IHD
framingham
multigenerational study for risk factors of heart disease
risk fx for IHD
age male smoker (rapid reduction 2 yrs after quitting) HTN DM hypercholesterol fam Hx cocaine methamphetamine physical inactivity
levels of framingham risk
10 year risk**
low risk 20%
-aggressive risk modification
metabolic syndrome
risk fx with 2x increased CAD risk
insulin resistance hyperglycemia HTN elevated trigyceride low HDL obesity
conditional risk fx
homocysteine lipoprotein a hsCRP LDL particle size antioxidant size omega 3 FAs
MI risk fx
cholesterol smoking stress DM HTN obesity alcohol exercise veggies and fruit daily
diagnostic testing for IHD
CPK
troponin
LDH
exercise stress test
pharm stress test
imaging augmentation
angiography
CT - coronary artery calcium score
HR max
220 - age
dobutamine
increases cardiac stress and oxygen demand
-in stress test
used to cause vasodilation coronary steal during stress test
adenosine
dipyridamole
gold standard for defining coronary occlusion
angiography
need to do other exam for CAD
if LBBB on EKG