Sex steroid drugs: Flashcards

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1
Q

levonorgestrel

A

up to 72 hours post-coitus.

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2
Q

ullipristal acetate

A

up to 120 hours post-coitus.

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3
Q

oestradial

A

stimulates breast and endometrial growth, stimulates production of progesterone receptors, decreases bone reabsorption, increases HDL levels, increases sodium and water retention and impairs glucose tolerance.

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4
Q

medoxyprogesterone

A

stimulates breast and endometrial growth, maintains pregnancy, inhibits production of oestrogen receptors, fluid retention and mood changes.

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5
Q

testosterone

A

stimulates male secondary characteristics, increased aggression, promotes hair growth and voice changes.

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6
Q

COCP

A

oestrogen inhibits FSH and progesterone inhibits LH, thus suppressing ovulation. progesterone also creates a thick cervical mucus hostile for sperm and implantation.

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7
Q

POP

A

thickens cervical mucus to prevent sperm entry.

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8
Q

Clomiphene

A

inhibits oestrogen binding in anterior pituitary, thus inhibiting the negative feedback needed for ovulation.

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9
Q

tamoxifen

A

binds to oestrogen receptors in the breast, to prevent cell division.

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10
Q

mifepristone

A

partial agonist of progesterone, blocks receptors.

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11
Q

raloxifene

A

oestrogen receptor modulator, acts on bone to cause oestrogenic effects, thus protecting against osteoporosis.

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