Anti-obesity drugs and thyroid drugs: Flashcards

1
Q

orlistat

A

gastric and pancreatic lipase inhibitor.

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2
Q

sibutramine

A

NA and serotonin re-uptake inhibitor, thus promoting satiety and suppressing appetite.

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3
Q

levothyroxine

A

form of thyroxine (T4). T4 and T3 bind to thyroid receptor proteins in the cell nucleus and cause metabolic effects through the control of DNA transcription and protein synthesis.

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4
Q

carbimazole

A

prevents thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing production of thyroid hormones T3 and T4.

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