Anti-obesity drugs and thyroid drugs: Flashcards
1
Q
orlistat
A
gastric and pancreatic lipase inhibitor.
2
Q
sibutramine
A
NA and serotonin re-uptake inhibitor, thus promoting satiety and suppressing appetite.
3
Q
levothyroxine
A
form of thyroxine (T4). T4 and T3 bind to thyroid receptor proteins in the cell nucleus and cause metabolic effects through the control of DNA transcription and protein synthesis.
4
Q
carbimazole
A
prevents thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing production of thyroid hormones T3 and T4.