Lipid lowering drugs:

Question 1

atorvastatin

Answer 1

inhibits HMG-CoA reductase, thus inhibiting the formation of cholesterol. Reduces plaques, improves endothelial cell function and reduces thrombotic risk.

Question 2

fibrates

Answer 2

increases production of lipoprotein lipase, thus more fats broken down into fatty acids and glycerol.

Question 3

nicotinic acid

Answer 3

inhibits lipoprotein A synthesis, which raises HDLs.

Question 4

Ezetimibe

Answer 4

inhibits intestinal cholesterol absorption, thus reducing circulating cholesterol and increasing expression of LDL receptors.