Nervous system drugs:

Question 1

first line of Parkinson’s drugs?

Answer 1

L-DOPA and DOPA decarboxylase inhibitor.

Question 2

other drugs used to treat Parkinson’s?

Answer 2

anticholinergics- treat tremor but no effect on bradykinesia.
dopamine receptor agonist.

Question 3

Mao type B inhibitors

Answer 3

inhibit breakdown of dopamine.

Question 4

COMPT inhibitors

Answer 4

doesn’t cross BBB, so prevents peripheral breakdown of L-DOPA to increase availability CNS.

Question 5

treatment for myasthenia gravis?

Answer 5

acetylcholinesterase inhibitors.

Question 6

SSRIs (fluoxetine)

Answer 6

block serotonin reuptake pump, causing accumulation of serotonin in the synaptic cleft.

Question 7

TCA

Answer 7

act on many neurotransmitters, to inhibit uptake.

Question 8

what drug is used in treatment of OCD?

Answer 8

clomipramine

Question 9

other anti-depressants.

Answer 9

SNRIs.

Question 10

Anti-psychotic drugs:

Answer 10

atypical- risperidone- first line.
typical (haloperidol)
atypical- clozapine- third line.

Question 11

anti-anxiety drugs

Answer 11

benzodiazepines

Question 12

mood stabiliser drugs

Answer 12

lithium
anti-epileptic drugs
atypical anti-psychotics.

Question 13

how do you treat Alzheimer’s dementia?

Answer 13

AchE inhibitors

NMDA antagonist.