Antivirals and Antibiotics: Flashcards

1
Q

M2 ion channel blockers (amantadine)

A

block ion channel to prevent H influx.

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2
Q

Neuraminidase inhibitor (zanamivir)

A

sialic acid analogues bind with great affinity to neuraminidase, preventing it from cleaving and stopping the new virus being released.

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3
Q

Quinolones

A

prevent DNA replication.

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4
Q

Folic acid antagonists (trimethoprim)

A

prevents formation of DNA precursors.

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5
Q

Aminoglycosides (gentamicin)

A

binds to 30s ribosomal subunits.

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6
Q

macrolides (erythromycin)

A

inhibit peptidyl transferase.

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7
Q

tetracyclines (doxycyline)

A

inhibit aminoacyl-tRNA binding.

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8
Q

beta-lactams (penicllin and cephalosporin)

A

beta-lactamase inhibitors.

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9
Q

glycopeptides (vancomyocin)

A

bind to amino acids in cell wall to prevent further additions.

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10
Q

Drugs used to treat TB.

A

Rifampicin
isoniazid
pyrazinamide
ethambutol

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11
Q

how to treat fungi?

A

topical azoles.

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12
Q

Antimalarials

A

chloroquine, metronidazole.

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13
Q

how to treat H.pylori infection?

A

PPI
clarithromycin
amoxicillin

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