Antivirals and Antibiotics: Flashcards
M2 ion channel blockers (amantadine)
block ion channel to prevent H influx.
Neuraminidase inhibitor (zanamivir)
sialic acid analogues bind with great affinity to neuraminidase, preventing it from cleaving and stopping the new virus being released.
Quinolones
prevent DNA replication.
Folic acid antagonists (trimethoprim)
prevents formation of DNA precursors.
Aminoglycosides (gentamicin)
binds to 30s ribosomal subunits.
macrolides (erythromycin)
inhibit peptidyl transferase.
tetracyclines (doxycyline)
inhibit aminoacyl-tRNA binding.
beta-lactams (penicllin and cephalosporin)
beta-lactamase inhibitors.
glycopeptides (vancomyocin)
bind to amino acids in cell wall to prevent further additions.
Drugs used to treat TB.
Rifampicin
isoniazid
pyrazinamide
ethambutol
how to treat fungi?
topical azoles.
Antimalarials
chloroquine, metronidazole.
how to treat H.pylori infection?
PPI
clarithromycin
amoxicillin