Corticosteroids: Flashcards

1
Q

glucocorticoids (cortisol, prednisolone)

A

stimulates glycogenesis, gluconeogenesis, proteolysis and lipolysis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

mineralcorticoids (aldosterone)

A

increase number of ENac channels in the late DCT and collecting duct.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

why can corticosteroids be used as anti-inflammatory drugs?

A

inhibit B and T cell responses, reduce transcription of cytokines and phagocytes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How do these steroids work? (corticosteroids)

A

crosses cell membrane and binds to a steroid receptor. the steroid then enters the nucleus and binds to the hormone response element on DNA which can switch on/off transcription of proteins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly