Anti-epileptic drugs: Flashcards
1
Q
benzodiazepine (lorazepam)
A
first line for status epilepticus, bind to GABA receptors and have positive allosteric effects which increase chloride reflux.
2
Q
IV phenytoin
A
voltage-gated Na channel blocker.
3
Q
carbamazepine
A
voltage-gated Na channel blocker.
4
Q
lamotrigine
A
voltage-gated Na channel blocker.
5
Q
valproate
A
voltage-gated Na channel blocker and weak inhibition of GABA inactivation enzymes and stimulates GABA synthesising enzymes.
6
Q
IV flumazenil
A
reverses benzodiazepine overdose.