Anti-epileptic drugs: Flashcards

1
Q

benzodiazepine (lorazepam)

A

first line for status epilepticus, bind to GABA receptors and have positive allosteric effects which increase chloride reflux.

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2
Q

IV phenytoin

A

voltage-gated Na channel blocker.

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3
Q

carbamazepine

A

voltage-gated Na channel blocker.

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4
Q

lamotrigine

A

voltage-gated Na channel blocker.

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5
Q

valproate

A

voltage-gated Na channel blocker and weak inhibition of GABA inactivation enzymes and stimulates GABA synthesising enzymes.

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6
Q

IV flumazenil

A

reverses benzodiazepine overdose.

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