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🦠SELF DEFENSE🦠 > Session 8 > Flashcards

Session 8 Flashcards

Hemostasis part 2 - Coagulation factors and interpretation of data

1
Q

Which blood collection tube would be the best for coagulation factor testing?
a. Citrate, blue top tube
b. EDTA, purple top tube
c. Heparin, green top tube
d. No additive, red top tube

A

Citrate, blue top tube

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2
Q

You are reviewing the following coagulation panel in a critically ill patient with evidence of bleeding.
ACT: Prolonged
aPTT: Prolonged
PT: Prolonged
Platelets: Decreased
FDPs: Positive at 1:20
Which of the following best explains the coagulopathy in this patient?
a. Disseminated intravascular coagulation (DIC)
b. Factor VII deficiency
c. Factor X deficiency
d. Hemophilia A

A

Disseminated intravascular coagulation (DIC)

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3
Q

Which cofactor is essential for the activation of certain coagulation factors, whereby a lack of this cofactor will lead to coagulation abnormalities?
a. Fibrinogen
b. Plasmin
c. Vitamin C
Correct response
d. Vitamin K

A

d. Vitamin K

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4
Q

What is an anti-thrombotic activity of thrombin?
a. Activation of fibrinolysis inhibitors
b. Degradation of activated clotting factors
c. Generation of fibrin from fibrinogen
d. Promotion of platelet aggregation

A

Degradation of activated clotting factors

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5
Q

Which of the coagulation pathways is initiated by release of Tissue Factor (tissue thromboplastin, Factor III)?
a. Common pathway
b. Extrinsic pathway
c. Intrinsic pathway
d. Primary hemostasis

A

Extrinsic pathway

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6
Q

What is true about fibrinolysis?
a. Factor XIII is responsible for breaking down polymerized fibrin during fibrinolysis.
b. Fibrinolysis begins only after the clot grows to the diameter of the vessel lumen.
c. Plasmin, the enzyme responsible for fibrinolysis, is always present in the blood in its active form.
d. Thrombin acts to inhibit activation of fibrinolysis early in clot formation.

A

Thrombin acts to inhibit activation of fibrinolysis early in clot formation.

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7
Q

One of your patients is an 11-year-old Siamese cat with Factor XII deficiency (a relatively common congenital deficiency in cats). Which coagulation test would you expect to be abnormal in this cat?
a. aPTT
b. FDPs
c. Platelet count
d. PT

A

aPTT

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8
Q

The endpoint of which coagulation test is a platelet plug?
a. ACT
b. aPTT
Correct response
c. BMBT
d. PT

A
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9
Q
A
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10
Q
A
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11
Q

Which blood collection tube would be the best for coagulation factor testing?
a. Citrate, blue top tube
b. EDTA, purple top tube
c. Heparin, green top tube
d. No additive, red top tube

A

Citrate, blue top tube

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12
Q

You are reviewing the following coagulation panel in a critically ill patient with evidence of bleeding.
ACT: Prolonged
aPTT: Prolonged
PT: Prolonged
Platelets: Decreased
FDPs: Positive at 1:20
Which of the following best explains the coagulopathy in this patient?
a. Disseminated intravascular coagulation (DIC)
b. Factor VII deficiency
c. Factor X deficiency
d. Hemophilia A

A

Disseminated intravascular coagulation (DIC)

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1
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13
Q

Which cofactor is essential for the activation of certain coagulation factors, whereby a lack of this cofactor will lead to coagulation abnormalities?
a. Fibrinogen
b. Plasmin
c. Vitamin C
d. Vitamin K

A

Vitamin K

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14
Q

What is an anti-thrombotic activity of thrombin?
a. Activation of fibrinolysis inhibitors
b. Degradation of activated clotting factors
c. Generation of fibrin from fibrinogen
d. Promotion of platelet aggregation

A

Degradation of activated clotting factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which of the coagulation pathways is initiated by release of Tissue Factor (tissue thromboplastin, Factor III)?
a. Common pathway
b. Extrinsic pathway
c. Intrinsic pathway
d. Primary hemostasis

A

Extrinsic pathway

How well did you know this?
1
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2
3
4
5
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16
Q

What is true about fibrinolysis?
a. Factor XIII is responsible for breaking down polymerized fibrin during fibrinolysis.
b. Fibrinolysis begins only after the clot grows to the diameter of the vessel lumen.
c. Plasmin, the enzyme responsible for fibrinolysis, is always present in the blood in its active form.
d. Thrombin acts to inhibit activation of fibrinolysis early in clot formation.

A

Thrombin acts to inhibit activation of fibrinolysis early in clot formation.

17
Q

One of your patients is an 11-year-old Siamese cat with Factor XII deficiency (a relatively common congenital deficiency in cats). Which coagulation test would you expect to be abnormal in this cat?
a. aPTT
b. FDPs
c. Platelet count
d. PT

A

aPTT

18
Q

The endpoint of which coagulation test is a platelet plug?
a. ACT
b. aPTT
c. BMBT
d. PT

A

BMBT

19
Q

What type of bleeding is a clinical sign associated with disorders of secondary hemostasis?
a. Ecchymosis
b. Epistaxis
c. Hemarthrosis
d. Petechiae

A

Hemarthrosis

20
Q

The key enzyme responsible for fibrinolysis is: __________.
a. Antithrombin III
b. Fibrinogen
c. Plasmin
d. von Willebrand factor

A

Plasmin

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