Session-10

Question 1

You diagnose Edward, a 3-month-old kitten, with feline panleukopenia virus. Panleukopenia virus can result in severe neutropenia (decrease in circulating neutrophils) in cats. You remember from your first-year Self Defense class that administration of what growth factor can directly stimulate neutrophil production?
a. G-CSF
b. Thrombopoietin
c. M-CSF
d. Interleukin-4 (IL-4)

Answer 1

G-CSF

Question 1

How long does it take for neutrophils to mature?
a. 10 hours
b. 1-2 days
c. 5 days
d. 2 weeks

Answer 1

5 days

Question 2

What is the order in which neutrophils transit from the bone marrow to the tissue?
a. Proliferation pool → storage pool → maturation pool → circulating pool → marginating pool → tissue
b. Proliferation pool → maturation pool → storage pool → marginating pool → circulating pool → tissue
c. Proliferation pool → maturation pool → storage pool → circulating pool → marginating pool → tissue
d. Maturation pool → proliferation pool → storage pool → circulating pool → marginating pool → tissue

Answer 2

Proliferation pool → maturation pool → storage pool → circulating pool → marginating pool → tissue

Question 3

Which cell line(s) produce(s) a terminally differentiated cell that eventually matures in the tissues after leaving circulation?
a. Monocytes and neutrophils
b. Eosinophils and basophils
c. Monocytes and B-lymphocytes
d. Neutrophils and B-lymphocytes

Answer 3

Monocytes and B-lymphocytes

Question 4

From which pool are blood samples collected?
a. The maturation pool
b. The marginal pools
c. The circulating pool
d. The storage pool

Answer 4

. The circulating pool

Question 5

When you take a blood sample from an excited cat in your clinic, what might you expect to see on the leukogram?
a. Neutrophilia with a left shift and lymphocytosis
b. Neutropenia and lymphopenia
c. Mature neutrophilia and lymphocytosis
d. Neutropenia with a left shift and lymphopenia

Answer 5

Mature neutrophilia and lymphocytosis

Question 6

Why can’t we run avian blood through our CBC analyzer?
a. Avian blood is much thicker than mammalian blood and would clog the analyzer.
b. Avian red blood cells and platelets are nucleated, leading to invalid results.
c. There are no reagents specific for bird blood.
d. Avian species cannot give sufficient volume blood volume to run a full CBC.

Answer 6

Avian red blood cells and platelets are nucleated, leading to invalid results.

Question 6

What is the most consistent finding in a corticosteroid leukogram in dogs and helps us to identify this leukogram?
a. Neutrophilia
b. Lymphocytosis
c. Lymphopenia
d. Left shift

Answer 6

Lymphopenia