Session 2- PI

Question 1

What is the primary function of erythrocytes?
a. Maintaining acid-base status
b. Host defense
c. Clotting of blood
d. Transport oxygen and carbon dioxide between the lungs and the tissues

Answer 1

Transport oxygen and carbon dioxide between the lungs and the tissues

Question 2

What is the only hematopoietic cell that can move between the blood and tissues and back again?
a. Monocyte
b. Erythrocyte
c. Lymphocyte
d. Neutrophil

Answer 2

Lymphocyte

Question 3

Where does hematopoiesis start for all blood cells?
a. Lymph nodes
b. Bone marrow
c. Liver
d. Thymus

Answer 3

b. Bone marrow

Question 3

You submit a bone marrow aspirate to the Veterinary Diagnostic Laboratory for an anemic patient. The report indicates that the patient has erythroid hyperplasia. What does this term mean?
a. Increase in the number of platelets
b. Increase in the number of red blood cells
c. Increase in the size of red blood cells
d. Decrease in number of red blood cells

Answer 3

Increase in the number of red blood cells

Question 4

You collect blood in a purple top tube containing EDTA. If you spin this blood down in a centrifuge, what do we call the liquid portion obtained? Do you expect it to contain coagulation factors?

Answer 4

Plasma; does contain coagulation factors

Question 5

When you collect blood for a CBC, what additional essential step must be taken?
a. Make and review a blood smear
b. Perform a serum chemistry
c. Make sure that the blood has clotted
d. Store a sample of blood for 48 hours

Answer 5

Make and review a blood smear

Question 6

What cannot be reliably trusted on the CBC readout as provided by the analyzer?
a. White blood cell count (WBC)
b. Leukocyte differential
c. Hematocrit (HCT)
d. Mean Cell Volume (MCV)

Answer 6

Leukocyte differential- need to do a blood smear to get these reliable results

Question 7

What are the most common sites utilized for collecting bone marrow samples from large animals and why?
a. Ribs and sternum; Sampling the sternum and ribs presents less danger to the veterinarian than other sites.
b. Ribs and sternum; Large animal species only produce hematopoietic tissue in the cavities of these bones.
c. Proximal femur, humerus, iliac crest; These sites are easy to access in these species.
d. Ribs and sternum; The cortex of long bones in these species are too thick and dense to sample effectively.

Answer 7

Ribs and sternum; The cortex of long bones in these species are too thick and dense to sample effectively.

Question 8

Which cell has the lowest mitotic rate?
a. Hematopoietic stem cell
b. Common lymphoid progenitor cell
c. Granulocytic progenitor cell
d. Metarubricyte

Answer 8

Hematopoietic stem cell

Question 9

Phoenix, a 7-year-old male neutered domestic short-hair cat, presents to your clinic for lethargy and pale mucus membranes. Following results of other diagnostics, you obtain a bone marrow sample, and the clinical pathology report indicates the presence of myelofibrosis (replacement of the bone marrow tissue with reticulum fibers). What findings might you expect on your CBC (complete blood cell count)?
a. Reduction in lymphocytes only (lymphopenia)
b. Erythrocytosis (increase in red blood cells)
c. Reduction in all three cell lines (pancytopenia)
d. No changes-Phoenix’s CBC will be completely normal

Answer 9

Reduction in all three cell lines (pancytopenia)

Question 10

What organ in the hemic-lymphatic system is primarily responsible for removing old, damaged, or parasitized red blood cells from circulation?
a. Bone marrow
b. Thymus
c. Lymph nodes
d. Spleen

Answer 10

Spleen

Question 11

What is a characteristic of the innate immune system?
a. More complex response
b. Very specific response
c. First line of defense
d. Delayed line of defense

Answer 11

First line of defense

Question 12

Which is part of the first barrier of the immune system?
a. Mucosal Associated Lymphoid Tissue (MALT)
b. B-lymphocytes
c. Lymph nodes
d. Mucociliary apparatus

Answer 12

Mucociliary apparatus -
Lymphoid is relating to ADAPTIVE immune system but we are looking for first barrier

Question 13

What is part of the thrombogram?
a. Mean Cell Volume (MCV)
b. Absolute eosinophil count
c. Hematocrit (HCT)
d. Mean platelet volume (MPV)

Answer 13

Mean platelet volume (MPV)

Question 14

If an animal has permanent damage to the megakaryocyte-erythroid progenitor cell, which cell line(s) would you expect to be affected?
a. Erythrocytes
b. Erythrocytes and platelets
c. Neutrophils and monocytes
d. Neutrophils
e. Platelets

Answer 14

Erythrocytes (erythroid progenitor cell) and platelets (megakaryocyte)