Serotonin Flashcards
1
Q
Lysergic acid diethylamide
A
LSD
5-HT2 agonist
Hallucinogen
2
Q
buspirone
A
partial 5HT1 agonist
anti axienty
3
Q
sumatriptan
A
5-HT1 agonist
tx- migraine, stops headache
Side effect- nausea, vomiting, angina, dizziness
4
Q
fluoxetine
A
serotionin reuptake inhibitor
tx- OCD, panic attacks
5
Q
phenelzine
A
Monoamine oxidase inhibitor
tx- depression and narcolepsy
side effect- food induced hypertensive crisis
6
Q
cyproheptadine
A
Serotonin antagonist
5-HT2 antagonist
Histamine H1 antagonist
tx- skin allergies, pruritus and urticaria
7
Q
ondansetron
A
5-HT3 antagonist
tx- chemotherapy induced nausea
8
Q
alosetron
A
5-HT3 antagonist
tx- diarrhea in women with IBS
9
Q
Seretonin
A
made from tryptophan
enzyme tryptophan hydroxylase-rate limiting
MAO
not made in platelets
converted to melatonin in pineal gland
90% in GI
10
Q
5-HT1
A
inhibit adenylate cyclase
11
Q
5-HT2
A
Phosphoinositide hydrolysis
