Renin Angiotensin

Question 1

aliskiren

Answer 1

Inhibits Renin activity
thus decrease in Ang I and II
Tx hypertension without changing HR

Question 2

losartan

Answer 2

AT1 Receptor blocker (ang II receptor)
causes vasodialation, anti proliferation and apoptosis
Reduces BP without increasing HR
decrease afterload
Tx- heart failure

Question 3

Captopril

Answer 3

ACE inhibitor
decrease ang II and increase bradykinin
tx hypertension and heart failure
Adverse effects- cough, rash, taste change, angioedema(allergic reaction).

Question 4

enalapril

Answer 4

ACE inhibitor
decrease ang II and increase bradykinin
tx hypertension and heart failure
Adverse effects- cough, rash, taste change, angioedema(allergic reaction).

Question 5

lisinopril

Answer 5

ACE inhibitor
decrease ang II and increase bradykinin
tx hypertension and heart failure
Adverse effects- cough, rash, taste change, angioedema(allergic reaction).

Question 6

spironolactone

Answer 6

Aldosterone antagonist
inhibits Na and H2O retention
Used as a diuretic to treat Hypertension and heart failure

Question 7

eplerenone

Answer 7

Aldosterone antagonist
inhibits Na and H2O retention
Used as a diuretic to treat Hypertension and heart failure

Question 8

propranolol

Answer 8

decreases renin release

Question 9

metoprolol

Answer 9

decreases renin release