Sepsis Flashcards

1
Q

what are some risk factors of sepsis

A
elderly and the very young
impaired immune system 
diabetics 
surgery in last 6 weeks 
breach of skin integrity 
Iv users 
catheters 
pregnancy and ASPLENIC
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2
Q

Colonisation

A

presence of a microbe in the human body that does not cause infection or a specific immune response

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3
Q

Infection

A

occurrence of inflammation due to the presence of a microbe

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4
Q

Septicaemia

A

presence of viable microbes in the blood

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5
Q

Patients with 2 or more of the following criteria are defined as having sepsis

A

temperature of more than or equal to 38 degrees or less than 36
HR above 100
RR above 20/min
Leukocyte count more than 16000 or less than 4000

PLUS
a documented infection site

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6
Q

where does sepsis present clinical signs

A
CNS 
GI 
Respiratory 
Haematology 
Renal 
Skin 
Cardivascular
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7
Q

What is the sepsis 6

A
  1. Take Blood cultures
  2. Measure accurate hourly Urine output
  3. Give intravenous Fluid challenges
  4. Give broad spectrum Antibiotics
  5. Measure serum Lactate and haemoglobin
  6. Administer high flow Oxygen.
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8
Q

Diagnosing Infection

A

Blood tests: WCC, CRP, platelets, clotting

  • Microbiology: Culture - blood, stool, urine, wound swab, tissue, CSF, sputum
  • Viral studies: e.g. NAAT / PCR
  • Serology: for antibodies
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9
Q

Treatment

A
  • Blood cultures before prescribing
  • Review once microbiology results available
  • IV antibiotics within 60 minutes of recognition of sepsis
  • IV fluids
  • Oxygen
  • Vasopressors
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