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Infection > Sepsis > Flashcards

Sepsis Flashcards

1
Q

What is sepsis

A

A life threatening condition that arises when the bodys response to infection injures its own tissue and organs

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2
Q

What is the pathophysiology of sepsis

A
  1. A complex interaction with the immune system and the pathogen
  2. Inflammatory responce of vasodialtion, increases permeabiity and migration of WBC
  3. Dysregulation of haemostasis
  4. Endothelial barrier is compromised so the WBC can get to the tissue
  5. Hypotension due to vascular component reducting
  6. Anaerobic respiration due to hypoperfusion
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3
Q

What can hypotension and hypoperfusion of tissue result in

A

Organ damage

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4
Q

What are examples of organ damage

A 
ARDS
Cardiomyopathy
AKI
Cholestasis
Caogulopathy 
Delirium 
Bone marrow supression
Myopathy
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5
Q

What are the organisms that can cause sepsis

A

Bacteria
Viruses
Fungi
Parasite

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6
Q

Which bacteria is most common that can cause sepsis

A

Bacteria

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7
Q

What are the common sources of sepsis

A 
Pneumonia
Meningitis 
Bloodstream infection
Skin or soft tissue infection
Catheter related infection 
UTI
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8
Q

On a NEWS score scale, which score suggests sepsis

A

Above 5

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9
Q

What features does the person have to suspect sepsis

A

Possible sepsis

Circulatory compromise/ unexplained deterioration

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10
Q

How do we risk stratisfy people

A

SOFA score

Q-SOFA score

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11
Q

When is the SOFA score used

A

In ITU

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12
Q

What does the Q-SOFA score look at

A

Altered mental status
High respiratory rate
Low blood pressure

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13
Q

What are the signs of sepsis in a patient

A 
Confusion
Sweating and clammy
Cool peripheries
Low urine ouput
Hypotension
High/low temperature
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14
Q

What is the method for treating sepsis

A

Sepsis 6

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15
Q

What does the sepsis 6 involve

A

Giving 3

Taking 3

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16
Q

What do we give in sepsis 6

A

Antibiotics
High flow oxygen
Fluid

17
Q

What do we take in sepsis 6

A

Urine output - measure
Lactate
Blood culture

18
Q

How do we monitor sepsis

A

Houryl observation
Look at urine output
GCS

19
Q

What are the post symptoms of sepsis

A 
Sadenss
Anxiety 
Difficulty swallowing
Difficulty sleeping
Poor memory 
Fatigue
20
Q

When giving hihg flow oxygen what oxygen saturation levels do we aim for

A

92%

21
Q

What type of fluid do we give in sepsis

A

Crystalloid

Infection (17 decks)

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