Respiratory Tract Infection Flashcards
What organisms cause the common cold
Rhinovirus
Coronoviruses
What are the clinical features of the common cold
Coryza Rhinnorhea Sore throat Cough Sneezing
What is the management of the common cold
Self limiting
No role for cough syrup
Avoid antibiotics
Avoid aspirin in children
What is the medical term for sore throat
Pharyngitis with or without tonsilits
Which organism can cause pharyngitis
Viruses
Bacteria
What are the important bacterial causes of pharyngitis
A beta haemolytic streptococcus\
Strep pyogenes
How do we diagnose group a strep pharyngitis
Throat swab
What happens to the throat swab
Gets placed onto a blood agar and is cultured
What happen around the bacteria colony for it to be classed as beta haemolysis
Haemoltysis of the blood
What colour would strep a stain with gram stain
Purple due to it being a gram positive cocci
How do we decide who to treat with pharyngitis
Feverpain score - people with high score are giving antibiotics
What is the managemnet of group a strep pharyngitis
Phenoxymethylpenicillin
Or macrolide if allergic to penicillin
What are the complications of strep a pharyngitis
Quinsy
Scarlet fever
Rheumatic fever
Post strep glomerulonephritis
What are the 2 main problems diptheria causes
- Airway obstruction
2. Toxin mediated disease so it causes myocarditis and neuropathy
How is diptheria treated
Penicillin
Anti toxin agents
What is glandular fever caused by
Ebstein barr virus (EBV)
What are the clinical features of glandular fever
Fever Malasia Sore throat Lymphadenopathy Splenomegaly Rash with amoxicillin
Which test do we use to diagnose glandular fever
Monospot test
What does monospot test look for
Antibodies for any virus
What is the specific test to diagnose glandular fever
Serology- igm, igg, EBNA
What does igm + mean
Patient has had the infection previously
What is the EBNA antibody positive
After 2 months
What is the management of glandular fever
Symptomatic
Avoid contact sport due to splenomegaly rupture risk
Which ogranism can cause otitis media and sinusitis
Virus
Step pneumonia
Haemophilus infleunza
What are the clincal features of otitis media and sinuisitis
Fever
Pain and tenderness over sinuses
What are the management of otitis media and sinusitis
Decongestants
Grommets to drain the pus out
What are the complications of otitis media and sinusitis
Mastoiditis
Meningitis due to streptococcus pneumonia
Which organism causes acute epiglottitis
Haemophilus influenza type b
What are the features of acute epiglottitis
Drooling
Dysphagia
Dysphonia
What is the management of acute epiglottitis
Intubation
Iv ceftriaxone
What are the 3 phases of whooping cough
Catarrhal phase
Paroxysomal phase
Convalescent phase
What occurs in the catarrhal phase
Person is highly infectious for 2 weeks
What occurs in the paroxysomal phase
2-6 weeks of intense coughing
What occurs in the convalescent phase
Chronic cough
What is the management of whooping cough
Macrolide
What is the diagnosis of whooping cough by
Serology
Pcr on throat swab
What is laryngotrachetitis (croup)
Inflammation of the larynx and the trachea
What are the symptoms of croup
Stridor
Barking cough
Hypoxia and tachynpnea
What is the management of croup
Paracetamol and oxygen
Dexamethasone
No antibiotics
Which type of people does bronchiolitis occur in
Children (6 months)
What are the symptoms of bronchiolitis
Snuffling
Fever and mild cough
Worse at night
Difficulty feeding
What is brocnhiolitis
Inflammation of the bronchioles
What is the diagnosis of bronchiolitis by
CXR
Nasopharyngeal aspirate or swab for pcr
What is the management for bronchiolitis
Fluid, nutrition and anti pyretics
Hypoxic if not feeding
What is an exacerbation of COPD
Change in volume of sputum: more, changed colour
Character of sputum
Breathlessness and wheeze
What organism can cause an exacerbation of COPD
Viruses: rhinovirus
Bacteria: strep pnuemonia, hamophilus, e.coli, klebsiella
What is the management of exacerbation of COPD
Salbutamol
Ipratropium
Prednisolone
Amoxicillin, doxycycline (antibiotics)
How can we prevent exacerbation of COPD
Vaccination
Regular inhalers
Smoking cessation
What are the features of pneumococcal pneumonia
Fever Productive cough Sob Sepsis: shock, hypoxia Focal crepitations
How do we diagnose pnuemococcal pneumonia
Blood and sputum culture
Urinary pneumomoccal antigens
What is the treatment of pneumococcal pneumonia
Benzypenicillin
How do we assess the severity of pneumococcal pneumonia
CURB65 score
Which organism can cause atypical pneumonia
Legionella
Mycoplasma
Chlaymdia
What are the symptoms of bronchiectasis
Daily cough Thick sputum production Multiple course of antibitoics Worsening sob Weight loss
What are the causes of bronchiectasis
Post infection: tb, pneumonia, whooping cough
Cystic fibrosis
Alpha 1 antitrypsin deficiency
Antibody deficiency
How do we diagnose bronchiectasis
- clinical picture as described
- High resolution ct
What is pleural empyema
Pus in the pleural cavity
What are the causes of pleural empyema
Post pnuemonia
Post surgery
What is the diagnosis of pleural empyema by
Culture
Ultrasond and pleural aspiration
What is the treatment of pleural empyema
Chest drain
Broad sprectum antibiotics
Then target cultured antibiotics
What is lung abscess
Pus within the lung tissue
What are the causes of lung abscess
Post pneumonia Surgery Foreign body aspiration Malignancy Emboli from elsewhere
What are the causes of hospital acquired pneumonia
Ventilator associated pneumonia on ITU
Immunocompromised patients
What happens to the organism of the normal flora
They change and are selected by use of antibiotics, you can get colonisation or pathogens
What is the treatment for early HAP
Co-amoxiclav
What is the treatment for late HAP
Piperacillin
What is aspiration pneumonia
Patients with impaired swallowing can aspirate on their own saliva and gastric secretions which can cause pneumonia
What organism cause aspiration pneumonia
Anareobes
Gram negative e.g e.coli
What are the treatment for aspiration pneumonia
Co-amoxiclav
Peg feeding tube
Speech and language therapy
What group of people is fungal pneumonia common in
Immunocompromised
What are the features of fungal pneumonia
Severe pneumonia
Lack of response to antibiotics
Atypical pattern on imaging
What organism can cause fungal pneumonia
Candida
Aspergillosis
Cyrptoccocus
What is the diagnosis if fungal pneumonia by
Sputum culture
Bronchoscopre for deep sample
Blood markers for galctomannan (aspergillus antigen)