Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infection > Fungal Infections > Flashcards

Fungal Infections Flashcards

1
Q

What type of cells are fungi

A

Eukaryotic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does the cell wall of fungi contain

A

Chitin

Glucans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What does the membrane of fungi contain

A

Ergosterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are examples of dermatophyte (tinea) infections

A

Tinea pedis

Tina corpus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is tinea pedis

A

Atheletes foot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is tinea corpus

A

Ring worms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the treatment of tinea infections

A

Topical terbinafine
Ketoconazole
Clotrimazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the most most significant/common candida

A

Candida albicans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What infections does candida albicans cause

A

Oral thrush
Vaginal thrush
Invasive candidiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which group of people are likely to get oral thrush

A

Immunocompromised
Denture weared
Inhaled steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the symptoms of oral thrush

A

Painful mouth
White plaques
Inflamed mucosa
Painful swallowing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the treatment of oral thrush

A

Nystatin mouth wash
Clotrimazole
Miconazole
Fluocanozole (oral)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What group of people is vaginal thrush common in

A

Increased ostreogen use
Antibitoics use
Steroids
Diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the symptoms of vaginal thrush

A

Vulva itching
Soreness
Discharge- whtie and thick
Dysuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the treatment of vaginal thrush

A

Clotrimazole cream

Oral fluconozole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What group of people does invasive candidiasis occur in

A

People with mucosal breaks e.g central line

Immunosupressed (neutropenic, septic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which candida is common in invasive candiasis

A

Non albicans candida

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What can the invasive candidiasis affect

A 
Spleen
Heart
Kidneys 
Eyes
Skin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How is the diagnosis of invasive candidasis made

A

Blood or tissue culture
Beta d glucan
PCR

20
Q

What is the treatment of invasive candidiassis by

A

Echinocandin
Fluconazole
Amphotericin b

21
Q

What is cryptococosis

A

Yeast

22
Q

How does cyrotococcosis infect

A

People can breath it into the lungs where macrophages usually kill it but when people have impaired immunity it can spread to cause pneumonia and cryptococcal meningitis

23
Q

Name a spore forming mould

A

Aspergillus

24
Q

How does aspergillus infect

A

By inhalation

25
Q

What disease can aspergillus cause

A

Allergic bronchopulmonary aspergillosis
Chronic pulmonary aspergillosis
Invasive aspergillosis

26
Q

What is allergic bronchopulmonary aspergillosis

A

Hypersensitivity airway reaction seen in asthma or cystic fibrosis

27
Q

What are the symptoms of ABPA

A

Asthma exacerbation
Brown mucous plugs
Haemoptysis

28
Q

How do we diagnose ABPA

A

Radiology

Immunology: raised total IGE, positive aspergillus IGE and eosinophillia

29
Q

What is the treatment of ABPA

A

Prednisolone

30
Q

What is chornic pulmonary aspergillosis

A

Infection of the lung tissue by aspergillus which shows slow progressve noldule formation, cavitation and fibrosis

31
Q

What people can chronic pulmonary aspergillosis occur in

A

People with
COPD
TB
I.e immune competent but with chronic lung disease

32
Q

What are the symptoms of chronic pulmonary aspergillosis

A

Weight loss
Cough
SOB
Haemoptysis

33
Q

What is the diagnosis if chronic pulmonary aspergillus by

A

Radiology

Microbiology: isolation of aspergills or aspergillus igg in serum

34
Q

What is the treatment of chronic pulmonary aspergillus

A

Itraxonazole
Surgery
Embolization

35
Q

What does invasive aspergillus occur in

A

People who have transplant and there is no neutrophils so aspergillus invades

36
Q

What is the diagnossis of invasive aspergillus by

A 
Histopathology 
Culture
Galactomannan serum
Beta d glucan
Pcr test
37
Q

What is the treatment of invasive aspergillus

A

Voriconazole

Amphotericin

38
Q

What is the type of fungi of mucomycosis

A

Mould

39
Q

Who does mucormycosis usually affect

A

People with:
Haemotological malignancy
High dose steroids
DKA

40
Q

What type of infection does mucormycosis present with

A

Rhino-orbital cerebral and pulmonary infections

41
Q

What is the treatment of mucormycosis by

A

Radical surgery

Amphotericin b

42
Q

Name the group of antifungal drugs that can be used to treat fungal infection

A

Amphotericin b
Azoles
Echonocandins
Flucytosine

43
Q

What is the mechanism of action of amphotericin b

A

Binds to egosterol and forms pores in the cell membrane

44
Q

What is the mechanism of aciton of azole

A

Inhibits ergosterol synthesis and damages the cell fungal membrane

45
Q

What are the mechanism of action of echinocandins

A

Non competitive inhibitors of 1,3 beta d glucan in the cell wall and affect the cell wall cross linking by reducing it and weakening the cell wall

46
Q

What is the mechanism of action of flucytosine

A

Interferes with dna and protein synthesis (developed as potential tumout agent)

Infection (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions