Semester II, Weeks 6-7 (intestines, GI-assoc. organs) Flashcards
What are these structures?
How can you tell?
Crypts of Lieberkuhn in the duodenum
(AKA intestinal glands)
- can see villi so it’s not the stomach
- visible Brunner’s glands in the submucosa so it’s duodenal, not another part of the intestine
Because of the structures visible in the marked layer we know that the outermost (leftmost) unmarked layer has a certain name.
What is that name and why?
Tunica Adventitia
- because all but the first segment of the duodenum is retroperitoneal (so it’s not serosa)
(the structures in the marked layer are Brunner’s glands, so we know it’s the duodenum)
What are the circled structures called?
Folds of Kerckring
AKA plicae circulares
- large valvular flaps of the intestinal wall for increasing surface area
What are the general layers of the small intestinal wall?
- Tunica Mucosa
- epithelium
- lamina propria
- lamina muscularis mucosae
- Tela Submucosa
- Tunica Muscularis
- inner circular layer
- outer longitudinal layer
- Tunica Serosa/Adventitia
- tela subserosa
- peritoneum
What are the indicated cells here?
How can you tell?
Paneth Cells
- highly eosinophilic cells lining the bottom of intestinal glands
- release lysozyme
What layer are these cells part of?
How can you tell?
Similar cells can be found in a layer closer to the lumen… what layer is that?
Myenteric Plexus of Auerbach
- they are seen here between the inner circular and outer longitudinal layers of the tunica muscularis
- neurons in the submucosa make up Meissner’s Plexus
What is this organ?
How can you tell?
Jejunum
- has plicae circulares (Kerckring folds), villi and tunica muscularis but does not have Brunner’s glands (duodenal) or Peyer’s patches (ileal)
What is this organ?
How can you tell?
Ileum
- clear Peyer’s patches in the submucosa
- in a lower magnification, these patches are only on the anti-mesenteric side of the ileum
What are these two circled areas?
Lymphocyte Invasion
- extensions of Peyer’s patches into the tunica mucosa
What is this organ?
How can you tell?
Appendix
- MALT surrounding the entire organ
(unlike the Peyer’s patches’ one-sided MALT presence in the ileum)
What is this organ?
How can you tell?
What is the stain?
Liver
- clear polygonal lobules with central veins
- AZAN stain (note the slightly blue interlobular CT)
What is this organ?
What are the blue stained areas which intersect at in middle upper portion of the slide?
Liver (AZAN stain)
- interlobular connective tissue stains blue here because of the AZAN stain
What is this organ?
How can you tell?
Liver
- a portal triad is visible just below the pointer
- hepatocytes and sinusoids are visible in their characteristic cord-like formations (which run toward the central vein of each lobule in lower magnifcation)
What is this circled structure?
What are its contents?
How can they be differentiated?
Portal Triad
- interlobular artery - smaller, thicker walled blood vessel
- interlobular vein - larger lumen, thinner walled blood vessel
- interlobular bile duct - simple cuboidal/columnar epi.
What are the different vessels marked 1 through 3?
- Interlobular Vein
- Interlobular Artery
- Interlobular Bile Ducts