Self Study Modules Of Turberculosis- Targeted Testing And The Diagnosis Of Latent TB Infection And Turberculosis Disease

Question 1

Available testing methods for M.tuberculosis

Answer 1

• Mantoux tuberculin skin testing
• Interferon gamma release assays

Question 2

Two types of Interferon gamma release assays

Answer 2

• Quantiferon- TB gold in tube
• T-spot TB test ( T-spot)

Question 3

Mantoux tuberculin skin test

Answer 3

TST is administered by injection and you wait 48-72 hours for swelling.

Question 4

.1ml of tuberculin units of liquid Tuberculin are injected between the layers

Answer 4

Of skin on forearm

Question 5

Forearm should be examined

Answer 5

48-72 hours by HCW.

Question 6

Induration is what
Measurement of induration

Answer 6

Millimeters and swellings

Question 7

Erythema

Answer 7

Redness is not measured

Question 8

Induration of 5mm is considered positive for

Answer 8

• HIV
• recent contacts of people with infections TB
• People with organ transplants
• Other immunosuppressive patients

Question 9

Indurations of greater then 10 mm

Answer 9

• People who have recently come to US from areas where TB is common
• People who abuse drugs
• Mycobacteriology
• People who live or work in high risk congregates settings
• People with certain medical conditions that increase risk for TB ( silicosis, diabetes mellitus, severe kidney disease, certain types of cancer, and certain intestinal conditions
• children younger than 5 years of age
• infants, children, or adolescents exposed to adults in high risk categories

Question 10

Induration of more then 15mm

Answer 10

Is considered a positive reactions for people who have no known risk factors for TB.

Question 11

Occupational exposure

Answer 11

• For people with TB on the job.

Question 12

4th generation fluoroquinolone

Answer 12

Trovafloxacin, Gatifloxacin, and Moxifloxacin

Used for anaerobes.