Fungi Flashcards

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1
Q

What fungi causes black spots on the hair shaft?

A

Black piedra is caused by Piedraia hortae

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2
Q

What causes white spots on the hair shaft?

A

Trichosporon beigelii that causes White piedra

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3
Q

tricopyton causes infection in the…

A

hair, skin & nails

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4
Q

Microsporum causes infection of…

A

the skin and hair

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5
Q

epidermophyton causes infection of…

A

skin & nails

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6
Q

you must use oil or oil saturated paper to recover ____________.

A

M. furfur

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7
Q

coccidioidomycosis/valley fever is caused by?

A

Coccidiodes immitis

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8
Q

___________ serology isnt useful because of cross reactivity and antigen detection is not sensitive

A

Blastomyces

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9
Q

some strains have proteases

A

Paracoccidioides brasiliensis

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10
Q

_______________ causes sporotrichosis (rose garderner’s disease) and is usually just subcutaneous

A

Sporothrix schenkii

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11
Q

Trychophyton rubrum is urease __________.

A

negative

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12
Q

T. mentagrophytes is urease ___________. and can penetrate hair.

A

positive

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13
Q

True or false:

rubrum and mentagrophytes difficult to differentiate by morphology alone

A

True

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14
Q

______________ produces ruby red pigment in Potato Dextrose Agar (PDA)

A

T. rubrum

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15
Q

T. mentagrophytes produces what pigments?

A

red to orange to reddish brown pigment

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16
Q

two or more morphologically distinct anamorphs produced

A

Synanomorphs

17
Q

used for any specimen where the teleomorph and one or more anamorphic state is present

A

Holomorph

18
Q

All molds are handled within a Class ___ safety cabinet.

A

II

yeasts can be handled on a bench top (safe)

19
Q

Antifungal agent:

Binds ergosterol, increases cell permeability, leading to leakage of cellular contents and cell death

A

Polyenes: Amphotericin B

20
Q

Antifungal agent:

Impair ergosterol synthesis in the cytoplasmic membrane

A

Azoles: fluconazole, itraconazole, voriconazole, posaconazole

21
Q

Antifungal agent:

Disrupts pyrimidine metabolism in the cell nucleus

A

Nucleoside analog – flucytosine

22
Q

Antifungal agent:

Inhibits formation of 1,3 glucan which is part of the cell wall

A

Echinocandin – caspofungin and micafungin

23
Q

Antifungal agent:

Disrupts the fungal cell membrane (squalene oxidase)

A

Allylamine – terbinafine