Fungi Flashcards
What fungi causes black spots on the hair shaft?
Black piedra is caused by Piedraia hortae
What causes white spots on the hair shaft?
Trichosporon beigelii that causes White piedra
tricopyton causes infection in the…
hair, skin & nails
Microsporum causes infection of…
the skin and hair
epidermophyton causes infection of…
skin & nails
you must use oil or oil saturated paper to recover ____________.
M. furfur
coccidioidomycosis/valley fever is caused by?
Coccidiodes immitis
___________ serology isnt useful because of cross reactivity and antigen detection is not sensitive
Blastomyces
some strains have proteases
Paracoccidioides brasiliensis
_______________ causes sporotrichosis (rose garderner’s disease) and is usually just subcutaneous
Sporothrix schenkii
Trychophyton rubrum is urease __________.
negative
T. mentagrophytes is urease ___________. and can penetrate hair.
positive
True or false:
rubrum and mentagrophytes difficult to differentiate by morphology alone
True
______________ produces ruby red pigment in Potato Dextrose Agar (PDA)
T. rubrum
T. mentagrophytes produces what pigments?
red to orange to reddish brown pigment
two or more morphologically distinct anamorphs produced
Synanomorphs
used for any specimen where the teleomorph and one or more anamorphic state is present
Holomorph
All molds are handled within a Class ___ safety cabinet.
II
yeasts can be handled on a bench top (safe)
Antifungal agent:
Binds ergosterol, increases cell permeability, leading to leakage of cellular contents and cell death
Polyenes: Amphotericin B
Antifungal agent:
Impair ergosterol synthesis in the cytoplasmic membrane
Azoles: fluconazole, itraconazole, voriconazole, posaconazole
Antifungal agent:
Disrupts pyrimidine metabolism in the cell nucleus
Nucleoside analog – flucytosine
Antifungal agent:
Inhibits formation of 1,3 glucan which is part of the cell wall
Echinocandin – caspofungin and micafungin
Antifungal agent:
Disrupts the fungal cell membrane (squalene oxidase)
Allylamine – terbinafine
