Seizures PEDIATRICS Flashcards
Refractory status epilepticus
Used 1 :1st Line Drug
Used 1 :2nd Line Drug
Still seizure not controlled
Epilepsy syndromes by Age
🧠⚡WOD FEB LARJ ⚡
🧠⚡LG - 2 Letters and LG SYNDROME= 2+8=10 Letters ⚡
<1 yr:
Ohtahara syndrome
Dravet Syndrome
West Syndrome.
6month-5yrs: FEBRILE SEIZURES
2yrs-10yrs: Lennox Gestaut syndrome
> 5 yrs-8yrs : Absence Seizure
> 5yrs to Adolescent: Rolandic Seizures
> 10yrs Adolescents : Juvenile Myoclonic Epilepsy
Early Infantile Epileptic Encephalopathy
Ohtahara Syndrome
Ass. with Brain Malformation
Mutation in DRAVET SYNDROME
🧠⚡DRAVid SCANS the field ⚡
SCN1A GENE DEFECT
1ALPHA- SODIUM CHANNEL
KCNJ10 MUTATION IS ASSOCIATED WITH
🧠⚡Kyoto and ChiNa in EAST ⚡
East Syndrome
EAST SYNDROME
🧠⚡ SeSAME⚡
Seizures
SNHL
Ataxia
Mental Retardation
Electrolyte imbalances
West Syndrome
🧠⚡ West(US) Great beacuse of –HIMS (Mens)⚡
Hypsarrythmic pattern on EEG
Infantile Spasm
Mental Retardation
Salaam Spells
LGS
🧠⚡ SIM⚡
Slow spike and wave pattern
Intractable Seizures
Multiple seizure types
Mental Retardation
DOC FOR DRAVET SYNDROME/JME/ ABSENCE SEIZURES
🧠⚡DRAVID aka JaMMY aka WALL ⚡
VALPROATE
DOC of ABSENCE SEIZURE
> 2 yrs : VALPROATE
< 2 yrs : ETJOSUXIMIDE
Landau Kleffner Syndrome
🧠⚡ L⚡
🧠⚡ Age - Rotate L to form 7⚡
Abruptly lost ⭐ LANGUAGE comprehension and Verbal Comprehension
Anger
Frustration
⭐ AGE 3-7 yrs
BECTS aka
⭐ ROLANDIC EPILEPSY
Benign Epilepsy with Centro-temporal spikes
Epilepsy that occurs in NIGHT
🧠⚡R = Raat ⚡
Rolandic Epilepsy
✨ tingling sensation in buccal mucosa or throat
⭐ tonic clonic contraction on one side of face
💊💉 MANAGEMENT West Syndrome
DOC: ACTH
In case of Tuberous Sclerosis patient
DOC: VIGABATRIN
High Dose steroids
PUFF of SMOKE APPEARANCE on Cerebral Angiography
MOYAMOYA DISEASE
MOYAMOYA Disease
Progressive cerebrovascular disorder caused by blockade of arteries at BASE of BRAIN AND BASAL GANGLIA
TANGLES OF BLOOD VESSELS SEEN
🧑🏻⚕️ Clinical Features of MOYA MOYA DISEASE
Stroke or recurrent TIA
Muscle weakness or Paralysis
Focal neurological deficits
DROP ATTACKS are associated with
JANZ SYNDROME
Genetic abnormality in JANZ/ JME
GABRA1
CLNC2
Myoclonin 1
Small muscles of Hand and foot involved in
Janz syndrome
Triggers for JANZ SYNDROME
Sleep deprivation
Alcohol
Photic stimulation
Reflex Seizures
⚡⚡ MOST COMMON Epilepsy in Young adults and adolescents
Janz syndrome
JME
Simple Febrile Seizures and Complex Febrile Seizures
🧠⚡SI =15 ⚡
🧠⚡Complex = F³ ⚡
⚡⚡ MOST COMMON type of Seizure in NEONATES
Subtle /Minimal
⚡⚡ MOST COMMON TYPE OF SEIZURE IN OLDER CHILDREN
GTCS
⚡⚡ MOST COMMON Etiology of Seizure in NEONATES
HIE
Hypoxia induced Encephalopathy
⚡⚡ MOST COMMON Etiology of Seizure in OLDER CHILDREN
Febrile Seizure
⚡⚡ MOST COMMON CAUSE of SEIZURE IN PRETERM
Intracranial HEMORRHAGE
🩺 IOC TRANSCRANIAL USG through Ant Fontanelle
Risk factor for RECURRANCE of FEBRILE SEIZURES
🧠⚡Major: ONCE Dhoni Fan ⚡
🧠⚡ Minor: Always MSD Fan⚡
Risk factor for subsequent Epilepsy after Febrile Seizures
🧠⚡ if 1ST FAN - He might develop EPILEPSY⚡
Indications for Febrile Seizures Prophylaxis
🧠⚡ F18⚡
Frequent Seizures
Family History ➕
First seizure at Low Temperature
Age <18months
Drugs used in prophylaxis of Febrile Seizure
3days
Oral CLOBAZAM in India
Oral Diazepam in World
💊💉 MANAGEMENT of Febrile Seizures
✨ Anti Epileptic diazepam lorazepam oral/ intranasal Midazolam/ per rectal Diazepam
✨ Antipyretics
EEG PATTERN IN ATYPICAL, TYPICAL AND JME
🧠⚡ A COMES 1st⚡
FIRES
More common in
Febrile Infection Related Refractory Epilepsy Syndrome
⭐ Males;
⭐ >5yrs AGE