MENINGITIS Flashcards

1
Q

Meningitis: CAUSES in Different AGE GROUPS
🧠⚡0-6: BEL ⚡
🧠⚡6m-6yr: SNEH ⚡
🧠⚡6yr-60yr: SNHE⚡
🧠⚡> 60yrs: SPL ⚡

A
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2
Q

⭐ NORMAL CSF VOLUME
⭐ NORMAL CSF PRESSURE
⭐ NORMAL CSF CELL COUNT
⭐ NORMAL CSF PROTEIN
⭐ NORMAL CSF GLUCOSE

A

⭐ NORMAL CSF VOLUME
🎯 150ml

⭐ NORMAL CSF PRESSURE
🎯 90-180 mm H2O

⭐ NORMAL CSF CELL COUNT
🎯 < 5 cell

⭐ NORMAL CSF PROTEIN
🎯 15-45

⭐ NORMAL CSF GLUCOSE
🎯 60-80% of Blood Glucose

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3
Q

Differentiate BETWEEN Acute Pyogenic, Acute Viral & Tuberculous MENINGITIS

A
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4
Q

Indications of LUMBAR PUNCTURE
🧠⚡M²ISS DM ⚡

A

🎯 DIAGNOSTIC

  1. INFECTIONS
    ✨ Meningitis
    ✨ Encephalitis
  2. SUBARACHNOID HEMORRHAGE
  3. MALIGNANCY: Metastatic & 1°
  4. DEMYELINATING conditions:
    ✨ MS
    ✨ SSPE
  5. GBS
  6. SPINAL CORD BLOCKAGE
  7. MYELOGRAPHY

🎯 THERAPEUTIC
1. Spinal Anaesthesia & Epidural Anaesthesia

  1. CSF Drainage in NORMAL PRESSURE HYDROCEPHALUS
  2. INTRATHECAL INJECTION of CHEMOTHERAPEUTIC DRUG
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5
Q

🚫 CONTRAINDICATION of LUMBAR PUNCTURE

A
  1. Raised ICP
  2. Coagulopathy
  3. Infection at Injection site
  4. Bone deformity at Injection site
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6
Q

Substance more in CSF than Blood

A
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7
Q

Causes of LOW GLUCOSE in CSF

A
  1. Pyogenic MENINGITIS
  2. TUBERCULOUS MENINGITIS
  3. Fungal MENINGITIS
  4. Carcinomatous MENINGITIS
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8
Q

Causes of ELEVATED CSF PROTEIN

A
  1. MENINGITIS
  2. ABSCESS BRAIN
  3. TUMOUR: Brain or SPINAL CORD Tumour
  4. GBS
  5. MS
  6. SYPHILIS
  7. HEMORRHAGE
  8. FROIN’S SYNDROME
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9
Q

Xanthochromasia

A

Yellowish appearance of CSF

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10
Q

Causes of XANTHOCHROMASIA

A
  1. Old SUBARACHNOID HEMORRHAGE
  2. Jaundice
  3. Froin SYNDROME
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11
Q

Froin SYNDROME

A
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12
Q

Albumino-cytological dissociation is seen in

🧠⚡FAG⚡

A

Increase in CSF PROTEIN without INCREASING CSF Cell count

F-FROIN’S LOCULATION SYNDROME A-ACOUSTIC NEUROFIBROMA G-GUILLIAN BARRE SYNDROME

✨ Non inflammatory degeneration of Brain Parenchyma
✨ Tumours
✨ Spinal Cord Compression

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13
Q

⚡⚡ MOST COMMON CAUSE of MENINGITIS

A

Streptococcus pneumoniae

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14
Q

Difference between:
✨ MENINGITIS
✨ Encephalitis
✨ Encephalopathy
✨ Acute Febrile Encephalopathy

A

✨ Meningitis
Meningeal signs present predominantly
Seizure Present/Absent

✨ Encephalitis
Sensorium affection (coma)
Seizures

⭐ Encephalitis: Inflammation of brain parenchyma

⭐ Encephalopathy: Noninflammatory diffuse cerebral dysfunction (altered sensorium due to any cause)

⭐ Acute febrile encephalopathy: A febrile illness with altered sensorium of ≤2 weeks duration in a previously well child. May have infectious or noninfectious causes

⭐ Meningitis: Inflammation of leptomeninges.

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15
Q

⚡⚡ MOST COMMON CAUSE of POST SHUNTING MENINGITIS

A

Staphylococcus epidermidis > > Staphylococcus aureus

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16
Q

⚡⚡ MOST COMMON CAUSE of MENINGITIS Post CRANIOTOMY, Head Trauma & CSF Rhinorrhea

A

Pseudomonas (Gram negative)

17
Q

Classical Triad of MENINGITIS

A

SHORT HISTORY (1 DAY) with Lethargy & Drowsiness

  1. Fever HIGH GRADE
  2. Neck Stiffness
  3. Altered Sensorium

    Headache
18
Q

Classical Tetrad of ENCEPHALITIS

A

Fever

Altered Sensorium

Focal Neurological Deficit

Seizure

19
Q

⚡⚡ MOST COMMON SYMPTOM OF MENINGITIS

A

Severe HEADACHE

20
Q

Characteristics of Headache in ACUTE BACTERIAL MENINGITIS

A

Frontal TIGHTNESS, feels like Compression

21
Q

🧑🏻‍⚕️ORDER of Clinical Features in Acute MENINGITIS

A

Tiredness
⬇️
Irritable
⬇️
LETHARGIC
⬇️
High Grade Fever with intermittent episodes of Vomiting

22
Q

Which type of MENINGITIS present SUBACUTELY?

A

✨ TB MENINGITIS
✨ FUNGAL MENINGITIS

23
Q

Classical Signs of MENINGITIS

A
  1. Neck Stiffness / Cervical RIGIDITY
  2. KERNIG’S sign
  3. BRUDZINSKI’s sign
24
Q
A

KERNIG’S sign
BRUDZINSKI’s sign

25
Q

Other Features of MENINGITIS

A
  1. Raised ICP
    ✨ Papilledema
    ✨ Projectile Vomiting
    ✨ 6th CN palsy
    ✨ Reduced level of Consciousness
    ✨ Cerebral Herniation
  2. Decerebrate Posturing
  3. Cushing Reflex: ⬇️ HR, ⬆️ BP, RR ⬆️
26
Q

Special features of MENINGOCOCCAL MENINGITIS

A

Rash: diffuse erythematous maculopapular

27
Q

Focal Seizures of ➕ in MENINGITIS indicates

A

Encephalopathy

28
Q

Meningism
Meaning

A

Classical constellation of symptoms and signs associated with irritation of the meninges.

29
Q

INTERMITTENT NECK STIFFNESS IS CHARACTERISTIC FEATURE OF

A

Arnold Chiari Malformation

30
Q

Causes of NECK STIFFNESS

A
  1. Meningism
    ✨ MENINGITIS
    ✨ SUB ARACHNOID HEMORRHAGE (SAH)
  2. MENINGISM Mimics
    ✨ Cervical Spondylosis
    ✨ After Cervical Fusion
    ✨ Impending TONSILLAR HERNIATION (⬆️ ICP)
    ✨ Acute DYSTONIC Reaction
    ✨ Tetanus
    ✨ Strychnine Poisoning
  3. INTERMITTENT: Arnold Chiari Malformation
31
Q

Imaging before LUMBAR PUNCTURE is done i

A
32
Q

NON-INFECTIVE CAUSES OF MENINGITIS
🧠⚡C²DS⚡

A
  1. Carcinomatous
  2. CTD
  3. Drugs
  4. Substances injected into SAH
33
Q

Causes of CARCINOMATOUS MENINGITIS

A
  1. Leukemia
  2. Lymphoma
  3. Myeloma
  4. Melanoma
  5. Breast Cancer
  6. Lung cancer
34
Q

CTDs causing MENINGITIS

A
  1. Behcet’s
  2. SLE
  3. Sarcoidosis
  4. Rheumatoid arthritis
  5. Sjogren’s
35
Q

DRUGS causing MENINGITIS

A

Sulphasalazine
Cyclosporine
Azathioprine

36
Q

Types of MENINGITIS based on HERNIATION

A

🎯 UNCOMPLICATED MENINGITIS
✨ Raised ICT ➕ NO IMPENDING HERNIATION
✨ Lumbar PUNCTURE DONE

🎯 COMPLICATED MENINGITIS
✨ RAISED ICT ➕ IMPENDING HERNIATION
✨ Lumbar PUNCTURE 🚫 CONTRAINDICATION