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3 NERVOUS SYSTEM > ANTERIOR HORN CELL DISORDERS > Flashcards

ANTERIOR HORN CELL DISORDERS Flashcards

1
Q

⚡⚡ MOST COMMON type of MND

A

AMYOTROPHIC LATERAL SCLEROSIS

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2
Q

UMN ➕ LMN MND

A

Amyotrophic Lateral Sclerosis

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3
Q

Pure LMN MND

A

⭐ Spinal Muscle Atrophy
⭐ Multi focal Motor Neuropathy

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4
Q

Pure UMN MND

A

Primary Lateral Sclerosis

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5
Q

Paraproteinemias is ASSOCIATED with

A

MMN

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6
Q

Lou Gehrig’s Disease

A

Amyotrophic Lateral Sclerosis

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7
Q

On an ATROPHIC or WASTED LIMB, if Reflexes are ⬆️ ⬆️

A

Amyotrophic Lateral Sclerosis

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8
Q

Weakness in ALS

A

Late feature
DISTAL Weakness

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9
Q

Bulbar Palsy vs Psuedo Bulbar palsy
🧠⚡JGT SO madarchod ⚡
🧠⚡ JG ⬆️ in Psudobulbar Palsy ⚡
🧠⚡ Emotional liability (incontinence) seen in Pseudobulbar palsy⚡

A
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10
Q

Basic Difference between Bulbar and PseudoBulbar palsy

A

Bulbar is LMN LESION of CN 9,10,11,12 (Cranial Nerve nuclei in Brainstem undergoes atrophy)

PseudoBulbar is U/L UMN LESION of CN 9,10,11,12 (Cortico-bulbar fibers involvement)

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11
Q

1st SYMPTOM OF BULBAR PALSY

A

Nasal twang and Nasal Regurgitation
⬇️
Flaccid Tongue and Fasiculations
⬇️
Flaccid Dysarthria

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12
Q

Bulbar DYSARTHRIA

A

Flaccid Dysarthria

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13
Q

PseudoBulbar Dysarthria

A

✨ Spastic Dysarthria
✨ Donald Duck speech
✨ Hot potato speech

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14
Q

Bulbar Onset Dysarthria

A

1st SYMPTOM is DYSARTHRIA

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15
Q

Never involved in ALS

A

✨ Sensory symptoms
✨ ANS
✨ BOWEL & BLADDER
✨ Cognition
✨ Extraocular muscles

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16
Q

EMG in ALS

A

Long duration Polyphasic Fasciculation potentials ➕ Fibrillation

17
Q

MRI in ALS

A

B/L symmetrical Hyper intensity in Corticospinal Tract

18
Q

Kennedy’s disease

A

X-linked Spinobulbar Muscle Atrophy
✨ Pure LMN lesion
✨ Progressive weakness of limbs (Distal > Proximal) & Bukhar Muscles
✨ Androgen insensitivity
✨ Tremors ➕
✨ Trinucleotide Repeats ➕

19
Q

Hirayama Disease
Benign Monomelic Amyotrophy

A

✨ Dura comes anteriorly & compresses the spinal cord
✨ C8-T1
✨ Upper Limb wasting, weakness & Fasiculations
✨ Presents like MND

20
Q

Hirayama Disease MRI

A
  1. Atrophy (OR) Thinning of Middle & Lower Cervical Spinal Cors
  2. ⬆️ Intensity in Epidural Space
21
Q

Madras MND

A

LMN > > UMN
PROXIMAL = DISTAL Involvement
Bifacial Weakness
Severe Tongue Involvement
Hearing Loss ➕

3 NERVOUS SYSTEM (40 decks)

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