Sedatives Flashcards
1
Q
What class of drug is Lorazepam?
A
Benzodiazepines
2
Q
What are the indications for Lorazepam?
A
Anxiety disorders, insomnia, epilepsy, seizure disorders
3
Q
What is the MOA of Lorazepam?
A
Potentiate GABA activity at GABAa receptor. Positive allosteric modulators, hyperpolarisation of cell via increased Cl-efflux
4
Q
What are the adverse effects of Lorazepam?
A
Ataxia, depression, drowsiness, hypotension, muscle weakness and sleep disorders
5
Q
What are the drug-drug interactions of Lorazepam?
A
Other CNS depressants
6
Q
How can you remember Lorazepam?
A