Diabetic Drugs

Question 1

What class of drug is Dapagliflozin?

Answer 1

Sodium-glucose co-transporter inhibitor

Question 2

What are the indications of Dapagliflozin?

Answer 2

Add on therapy to type 2 diabetes mellitus. HFrEF.

Question 3

What is the mechanism of action of Dapagliflozin?

Answer 3

Decreases glucose reabsorption from tubular filtrate. Increases urinary glucose excretion. Competitive reversible inhibition of SGLT-2 in PCT.

Question 4

What are the adverse effects of Dapagliflozin?

Answer 4

UTI, thirst, polyuria and pancreatitis

Question 5

What are the drug-drug interactions of Dapagliflozin?

Answer 5

Antihypertensive and other hypoglycaemic agents

Question 6

What can you use to remember Dapagliflozin?

Answer 6

Question 7

What is the class of Semaglutide?

Answer 7

Incretin mimetic

Question 8

What are the indications for Semaglutide?

Answer 8

TIIDM + weight loss

Question 9

Mechanism of action of Semaglutide

Answer 9

Increase glucose dependent synthesis of insulin secretion.
GLP-1 receptor agonist
Because of how they are made they are resistant to DPP-4

Question 10

What are the adverse effects of Semaglutide?

Answer 10

GI upset, decreased appetite with weight loss

Question 11

What can you use to remember Semaglutide?

Answer 11