Respiratory Flashcards
What class of drug is Salbutamol?
Short acting beta 2 agonist
What are the common indications of Salbutamol?
To relieve symptoms of asthma and COPD
What is the mechanism of action of Salbutamol?
Symptoms relief through reversal of bronchoconstriction
What are the adverse effects of Salbutamol?
Adrenergic, fight or flight effects, tachycardia, palpitations, anxiety and tremor
What are the drug-drug interactions of Salbutamol?
Beta blockers
How do you remember Salbutamol?
What class of drug is Theophylline?
Xanthines
What are the common indications of Theophylline?
Additional controller therapies in severe asthma and COPD
Used later when things aren’t being controlled well at all
What is the mechanism of action of Theophylline?
Selective inhibitor of phosphodiesterase and antagonists of adenosine receptors
Block vagally mediated contraction of airway smooth muscle
What are the adverse effects of Theophylline?
Dry mouth, urinary retention, dry eyes
What are the drug-drug interactions of Theophylline?
CYP450 inhibitors such as ciprofloxacin, fluoxetine and many antifungals.
Increase concentration of Theophylline.
How do you remember Theophylline?
