NSAIDs Flashcards

1
Q

What class of drugs is Celecoxib?

A

NSAIDs

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2
Q

What are the common indications of Celecoxib?

A

To reduce swelling and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis

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3
Q

What is the mechanism of action of Celecoxib?

A

Selective COX-2 inhibitor. The intention of COX-2 inhibitors was to avoid inhibition of homeostatic actions mediated by COX-1.

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4
Q

What are the adverse effects of Celecoxib?

A

Increase risk of MI (Decrease in PGI2 in coronary vasculature)

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5
Q

What are the drug-drug interactions of Celecoxib?

A

GI: Aspirin and glucocorticoid steroids and anticoagulants (PPIs should be considered)
Renal: ACEi, ARBs and diuretics

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6
Q

How do you remember Celecoxib?

A
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