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Drug Of The Day > GI Pharmacology > Flashcards

GI Pharmacology Flashcards

1
Q

What class of drug is Omeprazole?

A

Proton pump inhibitor

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2
Q

What are some common indications for Omeprazole?

A

Indigestion, heartburn and acid reflux

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3
Q

What is the mechanism of action of Omeprazole?

A

Irreversibly inhibit the H+/K+ ATPase in gastric parietal cells.
Final stage in the pathway- very significant reduction in acid secretion

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4
Q

What are the adverse effects of Omeprazole?

A

GI disturbance, abdominal pain, constipation, diarrhoea, headache, dizziness, drowsiness and confusion

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5
Q

What are the drug-drug interactions of Omeprazole?

A

Omeprazole is a CYP inhibitor- reduced clopidogrel action
PPIs can increase effects of warfarin and phenytoin

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6
Q

How can you remember Omeprazole?

A
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Drug Of The Day (18 decks)

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