(Section B: Immunology) Lecture 09: Introduction Flashcards
Innate vs. Adaptive
- Innate: Stays same, doesn’t learn
- Adaptive: Reacts faster and larger second time
Purpose of Immune Systems
- “Defense against Invader”
- “Self-nonself discrimination”
- “Detection of Danger/Damage”
- Achieve peace and harmony w/ our enemies”
Components of the Immune System
- Barriers
- Cells
- Soluble Molecules (Humoral)
What is the analogy used for components of the immune system?
- Barriers, “Wall”
- Soldiers, “Soldiers”
- Soluble Molecules (Humoral), “Weapons”
What types of barriers are there?
- Mechanical
- Chemical
- Microbial
- Nutritional
What the main cells in mechanical barriers?
Epithelial cells
Describe:
Epithelial cells
- Lines the surfaces of various tracts (stomach, throat, skin etc.)
How are epithelial cells joined? Why?
Prevent pathogens from entering
How do epithelial cells work as mechanical barriers?
- Regeneration
- Desquamation (shedding)
- Secretions (mucus etc.)
What is the first line of defense?
Skin
What are skin cells known as?
Keratinocytes
What do keratinocytes form?
The corneal layer (keratin “shield”)
What are goblet cells and where are they found?
Goblet cells makes mucus and secretions
Found in the lungs
What is responsible for moving things out (coughing) in lungs?
Cilia
What do chemical barriers include?
Includes enzymes