Second half of Chapter 6 Flashcards
Structure of the Hair and Follicle:Dermal papilla
Dermal papilla: bud of vascular connective tissue encased by bulb. Only source of nutrition for hair.
Structure of the Hair and Follicle: Hair matrix
Hair matrix—region of mitotically active cells immediately above papilla. Hair’s growth center.
Structure of the Hair and Follicle:Follicle
Follicle—diagonal tube that extends into dermis and possibly hypodermis
Structure of the Hair and Follicle: Epithelial root sheath
Epithelial root sheath. Extension of the epidermis lying adjacent to hair root. Widens at deep end into bulge—source of stem cells for follicle growth.
Structure of the Hair and Follicle: Connective tissue root sheath
Connective tissue root sheath,Derived from dermis but a bit denser, Surrounds epithelial root sheath.
Structure of the Hair and Follicle: Hair receptors
Hair receptors—sensory nerve fibers entwining follicles.
Structure of the Hair and Follicle:Piloerector muscle (arrector pili)
Piloerector muscle (arrector pili)—smooth muscle attaching follicle to dermis. Contracts to make hair stand on end (goose bumps)
Hair Texture and Color: Texture
Texture—related to cross-sectional shape of hair.Straight hair is round, Wavy hair is oval, Curly hair is relatively flat.
Hair Texture and Color:Color
Color—due to pigment granules in the cells of the cortex.Brown and black hair is rich in eumelanin.Red hair has high concentration of pheomelanin.Blond hair has an intermediate amount of pheomelanin and very little eumelanin.Gray and white hair have little or no melanin. Air present in medulla.
Three stages of hair cycle:Anagen
Anagen: growth stage.90% of scalp follicles at a given time.Stem cells multiply.Root sheath cells above papilla form hair cells of hair matrix.Hair cells make keratin and die as they are pushed upward.
Three stages of hair cycle:Catagen
degeneration stage.Mitosis in hair matrix ceases and sheath cells below bulge die.Base of hair keratinizes into a hard club—club hair.Easily pulled out by brushing
Three stages of hair cycle: Telogen
resting stage.When papilla reaches the bulge
Hair Growth and Loss:We lose about 50-100 hairs daily
A club hair may fall out during catagen or telogen or be pushed out in the next anagen phase.In young adults, scalp follicles spend 6–8 years in anagen, 2–3 weeks in catagen, 1–2 months in telogen.
Hair growth
scalp hairs grow 1 mm per 3 days.Alopecia—thinning of the hair or baldness.
Pattern baldness
hair lost from select regions. Baldness allele is dominant in males and expressed when testosterone levels are high. Testosterone causes terminal hair on top of scalp to be replaced by vellus hair
Hirsutism
excessive or undesirable hairiness in areas that are not usually hairy.