First half of Chapter 6 Flashcards
What is the integumentary system
(Fancy name for skin) consists of skin and accesory organs; hair, nails and cutaneous glands.
Inspection
Inspection of the skin, hair and nails is significant part of a physical exam. Skin is the most vulnerable organ. Relieves more medical treatment than any other organ. Largest organ in our body.
Skin Thickness : Thick and Thin
Thick skin covers front of hands, bottoms of feet, has sweat glands but no hair follicles or sebaceous (oil) glands. Thin skin covers the rest possesses hair follicles, sebaceous glands and sweat glands.
Functions of the skin: resistance to trauma and infection
Keratin(predominant in skin), Dermacidin and defensins. Acid mantle.
Functions of the skin: Other barrier functions(keep out)
Water, UV radiation and harmful chemicals.
Functions of the skin: Vitamin D synthesis
Skin carries out of first step, liver and kidneys complete process.
Functions of the skin: sensation
Sensation: skin is an extensive sense organ. Receptors for temperature, touch, pain and more.
Functions of the skin: Thermoregulation
Thermoregulation:
Thermoreceptors(cool and conserve heat), Vasoconstriction/vasodilation. Perspiration.
Functions of the skin: Nonverbal communication
Nonverbal communication:
Facial expression
Importance in social acceptance and self image.
The Epidermis
Epidermis—keratinized stratified squamous epithelium
(inside cells but dead cells)
Includes dead cells at skin surface packed with tough keratin protein
Lacks blood vessels
Depends on the diffusion of nutrients from underlying connective tissue
Contains sparse nerve endings for touch and pain
Cells of the Epidermis: Stem cells
Undifferentiated cells that give rise to keratinocytes
In deepest layer of epidermis (stratum basale)
Cells of the Epidermis: Keratinocytes
Great majority of epidermal cells
Synthesize keratin
Cells of the Epidermis: Melanocytes
Melanocytes
Synthesize pigment melanin that shields DNA from ultraviolet radiation
Occur only in stratum basale but have branched processes that spread among keratinocytes and distribute melanin
Cells of the Epidermis: Tactile cells
Tactile cells: Touch receptor cells associated with dermal nerve fibers
In basal layer of epidermis
Cells of the Epidermis: Dendritic cells
Dendritic cells
Macrophages originating in bone marrow that guard against pathogens
Found in stratum spinosum and granulosum. Special type of immune cells.
Stratum basale (deepest epidermal layer)Layers of the Epidermis
Thin skin contains four strata; thick skin contains five strata
Stratum basale (deepest epidermal layer):A single layer of stem cells and keratinocytes resting on the basement membrane
Stem cells divide and give rise to keratinocytes that migrate toward skin surface to replace lost cells
Also contains a few melanocytes and tactile cells
Stratum spinosum (Layers of the Epidermis)
Several layers of keratinocytes joined together by desmosomes and tight junctions
Named for appearance of cells after histological preparation (spiny)
Also contains some dendritic cells.(resist pulling apart)
Layers of the Epidermis,Stratum granulosum
Stratum granulosum
Three to five layers of flat keratinocytes
Cells contain dark-staining keratohyalin granules(related to keratin)