Seborrhea

Question 1

Normal keratinization: takes _______ for cells to migrate from basal layer to the stratum corneum.
If that time is increased?

Answer 1

3 weeks

crusting and scaling

Question 2

function of sebum

Answer 2

controls bacteria. Loss of sebum function leads to secondary infection
regulated by hormones and under dietary influence

Question 3

primary seborrhea

breeds?

Answer 3

aka primary disease of keratinization

hyperkeratosis of cocker spaniels (nose and food pads crusty) also crusty where skin folds

Question 4

some cases (of primary keratinization) respond well to

Answer 4

vitamin A

just spaniels?

Question 5

zink responsive keratosis

Answer 5

crusting around eyes and nose and mouth

Question 6

endocrine dermatosis

Answer 6

atrophy of epidermis sebaceous gland and follicle, keratosis (plugged follicles - black heads classic cushing)

Question 7

secondary causes of seborrhea

Answer 7

allergy
environmental
neoplasm

Question 8

do ______ every time you have a skin case

Answer 8

cytology

so you dont have to guess if its bacteria yeast etc

Question 9

chance you get a positive skin scrape in a scabies dog?

Answer 9

50%

Question 10

mf

Answer 10

epithelial lymphoma

looks like bad pyoderma, dont get better with abx

Question 11

malassezia dermatitis

Answer 11

ventral neck!
clear demarcation!
imbalance of flora -> yeast infection becomes more obvious (can happen after giving abx)
**mutually beneficial to staph

Question 12

malassexia is very common in

Answer 12

allergic dogs
in florida bc hot and humid
with staph (mixed infection)

Question 13

malassezia clinical signs

Answer 13

smell
very itchy (no response to steroids!)
erythematous lesion on ventral neck
hyperpigmentation, lichenification, greasy after time

Question 14

yeast number do/do not?? correlate with severity of signs?

Answer 14

do not

Question 15

predisposed to malassezia

Answer 15

greasy skin folds
swimming a lot (wet coat)
florida

Question 16

malassezia in cats

Answer 16

chin acne

dirty ears

Question 17

treatment for yeast infection

Answer 17

• florida usually systemically
• ketoconazole suppresses p450 (drug interactions)
• itraconazole stays longer, less p450 suppression, tolerated in cats. at high doses causes vasculitis
• fluconazole, cheaper least effect on p450
• terbinafine (not designed for yeast so just no)
• topical - selsun blue(Se sulfide) not in cats!! ketoconazole shampoo, chlorhex, lime sulfur will help dry skin

Question 18

therapy of seborrhea complex

Answer 18

treat infection
shampoo to remove crusts (keratolytic) like benzoyl peroxide. 
good diet
vitamin A if priamry disease
steroids will reduce sebum production

Question 19

95% of seborrhea cases are

Answer 19

secondary