Sebaceous and Sweat Gland Disorders Flashcards
1
Q
Sebaceous Gland Locations
A
Fordyce is in mucous membranes
-Meibomian is eye lid
2
Q
Acne Pathogenesis
A
- Poral occlusion from epithelial proliferation or cosmetics leads to backup of sebum
- Sebum can rupture and lead to inflammatory cascade and oxygen radical release
- P Acnes digests triglycerides in sebum leading to further inflamation through TLR2 and type 4 reaction
3
Q
Other Acne Factors
A
- Hormones (DHT)
- Sebum productin
- PCOS
- Androgen tumor (21 alpha or other)
- Mechanical
- Drugs: Steroids,
- Tropical
4
Q
Other forms of acne
A
Common
- Congoblate
- Fulminans when there is systemic signs
- Excoriated
5
Q
Late Onset Acne
A
-Women on chin, nodular
6
Q
Topical Treatments
A
- Cleansing
- Benzoyl peroxid
- Alzaleic acid
- Topical Abx (Clinda, eryhtro)
- Retinoids (decrease TLR2 and normalize proliferation)
7
Q
Systemic
A
-Abx: Tetracylcines, minocylcine (lipid soluble, can lead to lupus and hyperpigmentation)
8
Q
Hormonal
A
OCP
-Spironolactone
9
Q
Isotretinoin
A
- Depression and suicidal ideation
- Intracranial HTN’
- Increased Scarring
10
Q
Scar Tx
A
- Lasers
- Dermabrasion
- Dermal Fillers
11
Q
Rosecea
A
- Older individuals
- No comodones
- Central Face
- Bacteria and sebum production are normal
12
Q
Papular Rosecea
A
-Abx: tetracycline, metrogel, azaleic acid
13
Q
Eryhtrodermotelangectatic
A
-Lasers
14
Q
Hyperhidrosis
A
- Generalized: look for systemic disease
- Localized associated with anxiety
15
Q
Hyperhidrosis Tx
A
- Aluminum Chloride
- Anticholinergics
- Ionotophoresis
- Botox
