Ch 13 Regional Dermatology Flashcards
Hair Growth
From placode mesenchymal cells in development
-Matrix is where melanocytes enter to cause color
Hair Cycle
-Anagen: Growth
-Catagen: Stop growth and clubbing of nail
Telogen: Shedding
Localized alopecia
Nonscarring: Areata, Traction, Human ringworm, Trichitlomania
Scarring: burns, LE, Ringworm non human, Aplasia Cutis, Cicatrical BC, Lichen planus, Sarcoid, pseudopalade
Areata
T cell infilatrate around hair bulbs
- HLA D and DOwns are associated
- Exclemation mark short hairs that taper towards scalp
- Syphilis may cause moth eaten hair, Margin is bad prognosis
Androgenetic
- Turn to velus
- Genetic
Traction
-May cause folliculitits and maybe scarring
RIngowowm
Scarring when non human strains
Scarring
Discoid LE
-Lichen Planus, morphea
Telogen Efflucivum
-Stress causes hairs to synchronize in catagen and then shed diffusely
Can be seen accompanying beaus lines
Hypohidriotic Ectodermal Dysplasia
- Teeth, Nails, Hair
- Can’t sweat
- XLR
Netherton
- Ca metabolism
- Also causes icthyosis
Hirsuitism
- Most is familial and idiopathic
- PCOS common cause
- If Virilization look for cause
Beckers Nevus
-Hypertrichosis
Cosmetics
PPD can cause contact allergy
Hypertrichosis
Anorexia Drugs: Cyclosporin Cutaneous Porphyrias FAS/Phenytoin Malignancy leads to lanugo
Nail Structure
Nail Fold which houses the matrix which makes that plate that sits on the bed
Onychogryphosis
-Thickening of the nail due to long term repeated trauama
CT diseases
Can cause telangectasia
Lichen Planus
Longitudinal Grooves with thinning
Acute Paronychia
- Pussy infection beneath nail, commonly near the matrix and initial plate
- Commonly caused by staph
Chronic Paronychia
Folds are tender and swollen, often occupational
Dermatophytes
- Commonly spread from tinea pedis
- Causes onychomycosis and crumbling of nail
- Don’t treat unless symptomatic
Periungal Fibroma
Tuberous sclerosis
Myxoid Cysts
Cause longtidunal groove in nail
Yellow Nail
-Associated with lyphatic obtrucion and pulmonary edema
Lichen Planus
Lacy white lesions in mouth
- Hep B/C should be checked as well as anti mitochondrial Ab
- Ulcerative form can lead to SCC
Candidiasis
- Treat with imidazoles
- Many causes
Pemphigus Vulgaris
- Mouth ulcer that doesn’t heal after time
- Also cicatricial pemphigoid causes mucus membrane lesions
Apthous Ulcers
Bechets, Chrons, Lupus, HIV, Vitamin Deficency
Peutz Jeghers
-Hyperpigented Macules on lips leads to internal malignancy
Benign Mouth Lesions
Fox-Fordyce are sebaceous glands in mouth
Mucocele
Pseudoxanthoma elasticum
Cowdens and HHT
Cowdens is fibrous papules
-HHT is telangectasia that can bleed
Black Hairy Tongue
Pigmentation and hypertrophy of filiform papillae leads to thick tongue
-Brush teeth
Smooth TOngue
Malabsorption
Fissure Tongue
Development, Downs, Trauma, Smoking
Geographical
Atopic, Familial, Psoriasis
-Tx with steroids
Hairy Leukoplakia
-EBV in pts with aids, give HAART
Macroglossia
-Amyloid, Thyroid
Glossydonia
-DM, Drymouth, Candidiasis
Furred Tongue
Hypertrophy of filiform papillae
Lichen Sclerosis
- Common on genetalia and anal region
- Can cause phimosis and lead to cancer
Lichen Planus
Can have lesions on genetalia,
- Look for wickhams striae
- Always confirm with mouth lesions
Pruritis
Many causes, don’t itch, can cause lichenification
Pearly penile papules
angiofibromas of glans
Fordyce
Ectopic sebacous on glans
fixed drug
commonly seen on penis
SCC
- Can arise from bowen disease or erythroplasia of queryt
- HPV associated
- Penectomy or topical immunotherapies or Mohs
Eryhtrasma
Brown patches on upper thighs, often in axillae as well
Inverse psoriasis
Gluteal fold
Interigo
Maceration