Ch 19 Disorders of Pigmentation Flashcards

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1
Q

Hypopigmentation Tyrosine

A

-Albinism, Pitaryasis Versicolor, PKU, Endocrine

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2
Q

Hypopigmentation Melanocytes

A

-Vitiligo, Piebaldism, Rubber

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3
Q

Hyperpigment Melanocytes

A

-Lentigo, Nevi, Melanoma, Cafe au lait

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4
Q

Hyperpigment Melanin

A

-Ephiledes, Race,

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5
Q

Albinism

A
  • Tyrosine + and - determined by hairpull

- + can recover some later inlife, negative never does

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6
Q

Piebaldism

A
  • KIT impairs melanocyte migration, white forelock

- CH and HP are variants

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7
Q

Vitiligo

A

-Destruction of melanocytes generalized is associated with autoimmunity and segmental is not

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8
Q

Ephiledes

A

-Freckle is increase in melanin with same number of melanocytes

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9
Q

Lentigo

A

Increased melanocytes

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10
Q

Nevi

A

Increased melanocytes along with melanoma

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11
Q

LentigoSyndromes

A
  • Puetz Jegher: Polyps in GI tract

- LEOPARD: heart and deafness

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12
Q

Drugs

A

Busulfan, bleomycin, minocycline

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13
Q

Dermal

A

Inflamation and mongolian stpots and drugs.

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