schizophrenia - neural correlates Flashcards
what is meant by neural correlates?
measurements of structures or functions of brain correlate with schizophrenia.
the original dopamine hypothesis
hyperdopaminergia
what is hyperdopaminergia?
high levels or activity of dopamine in the subcortex. access amounts of dopamine receptors in the broca’s area may lead to speech poverty or auditory hallucinations.
what is the updated hypothesis?
hypodopaminergia
what is hypodopaminergia?
low levels of dopamine in the prefrontal cortex could explain cognitive problems e.g. negative symptoms.
who proposed the new hypothesis
davis et al 1991
research support for positive symptoms
allen et al 2007 scanned the brains of people suffering from auditory hallucinations and compared them to a control group.
what was found in this study? - allen
lower activation levels in the superior temporal gyrus and anterior cingulate gryus were found in hallucination groups/
research support for negative symptoms
juckle et al 2006 measured activity levels in the ventral stratum (vs) in schizophrenia and found lower levels of activity than those observed in controls.
what was found in this study? - juckle
observed a negative correlation between the activity levels in the vs and the severity of overall negative symptoms.
