schizophrenia - biological explanations

Question 1

who said schizophrenia runs in families?

Answer 1

gottesman (1991)

Question 2

what does it mean by schizophrenia running in families?

Answer 2

if there is genetic similarity between family members can lead to the association with the likelihood of developing schizophrenia.

Question 3

what did gottesman say?

Answer 3

in mono-zygotic twins they share 100% of the same genes leading to a 48% chance of developing schizophrenia and in diozygotic twins they share 50% of the same genes which means there is a 17% risk of developing schizophrenia.

Question 4

candidate genes

Answer 4

schizophrenia is polygenic and is aetiologically heterogenous

Question 5

who has research supporting this?

Answer 5

ripke et al (2014)

Question 6

what did ripke study?

Answer 6

combined all previous data from genome-wide studies of schizophrenia, and had the genetic makeup of 37,000 patients and compared them to 113,000 controls and found 108 separate variation.

Question 7

what is the role of mutation?

Answer 7

it means when the male gamete called sperm mutates due to radiation, poison, and viral infections.

Question 8

brown et al 2002

Answer 8

positive correlation between parental age and risk of developing schizophrenia.