Schizophrenia Flashcards
What is the definition of schizophrenia?
A severe mental disorder characterised by disruption of cognitive and emotional functioning. It effects language, thoughts, perception and sense of self. The individual may hear voices and see visions.
What are some causes of schizophrenia?
1) genetics
2) brain damage
3) drugs and alcohol
4) childhood trauma
What is type 1 acute schizophrenia?
Obvious positive symptoms appear suddenly usually after stressful events
What is type 2 chronic schizophrenia?
The illness takes many years to form and gradual chnages of increased distrurbance and withdrawal occur. Characterised by negative symptoms.
What are the two manuals that diagnose schizophrenia?
ICD-10- produced by world health organisation and focuses on subtypes of schizophrenia
DSM-V- subtypes of schizophrenia were removed
What is the DSM-V criteria for schizophrenia?
A- need 2 or more of the following (delusions, hallucinations, disorganised speech, grossly disorganised/ catatonic behaviour, negative symptoms eg flattening/avolition)
B- since the onset of schizophrenia, one or more areas of functioning will be negatively affected eg work or interpersonal life.
C- continuous signs of disturbance will be present for 6 months or more. Symptoms from criteria a have been present for at least 1 month.
What is the meaning of positive symptoms?
This refers to excesses or symptoms that have been added to the patinet’s personality because they now have the illness of schizophrenia. These symptoms were not present when the person was healthy eg hallucinations and delusions.
What is the meaning of negative symptoms?
This refers to loss of normal functioning. The person will have a weakened ability to cope and manage everyday life. They lose the ability to do certain things eg speech poverty.
What are some positive symptoms of schizophrenia?
1) hallucinations - these can be auditory, visual, olfactory or tactile. They may see or hear things that do not actually exist.
2) delusions- they have a strong belief about something even though it’s based on mistaken and unrealistic views.
3) disorganised speech- the individual may make up random words or string random words together in a sentence that don’t make any sense.
4) catatonic behaviour- the patient have reduced reactions to environmental stimuli and can adopt rigid postures and standing completely still for long periods of time.
What are some examples of negative symptoms?
1) speech poverty- speech is lessened in terms of fluency and patinets thinking is slow and thoughts may be blocked. Usually leads to brief replies and minimal elaboration.
2) avolition - the patient have reduced interest and motivation to complete goals and are happy sitting around doing nothing.
3) affective flattening- the patient has restricted ability to respond to emotional stimuli. They may behave inappropriately in social situations eg laugh when told bad news.
4) anhedonia- general lack of interest in almost all activities and a lack of interest in pleasurable stimuli eg interacting with others.
What is reliability in schizophrenia?
Reliability is the level of agreement on the diagnosis by different psychiatrists across time. For the classification system to be reliable, different clinicians using the same system eg the DSM-V and should arrive at the same diagnosis for the individual.
What is validity in schizophrenia?
Validity is the extent to which schizophrenia is a unique syndrome with characteristics, signs and symptoms. For the classification system to be valid, it should be meaningful and classify a real pattern of symptoms, which result from a real underlying cause.
What is co-morbidity?
This refers to the extent that two or more conditions occur simultaneously in the same individual. For example a patient with schizophrenia may also be suffering from depression. This makes validity difficult because the symptoms of the two disorders may be the same for example depression and schizophrenia both involve low levels of motivation, so which causes issues in classifying the illness as schizophrenia. This also causes reliability issues as psychologists may diagnose one condition but not the other and there may be differences in diagnosis.
Evaluation of co-morbidity?
1) The DSM ans ICD can be criticised because they lack validity. There is too much of an overlap between schizophrenia, mood disorders and OCD so it is very easy to misdiagnose patients. A second opinion from a clinician may be necessary to make a valid diagnosis.
2) research conducted by SIM found that the diagnosis of schizophrenia can be invalid and unreliable because of co-morbidity. He found that 32% of 142 hospitalised schizophrenic patients had additional mental disorders which is an issue when diagnosing the illness.
3) it has been found that schizophrenia patients have used alcohol, drugs and suffer from substance abuse before they were diagnosed with the illness making it difficult to give a reliable and valid diagnosis of schizophrenia, because some of the symptoms of the illness are the same as those who use drugs and alcohol.
What is culture bias?
Culture has an influence on diagnosis and classification of schizophrenia. Luhrmann interviewed 60 adults with schizophrenia and found that though all reported hallucinations, patients from the USA reported the most significant negative symptoms compared to India and Ghana so culture has na affect on reliability of diagnosing schizophrenia.
Davidson and Neale explain that in Asian cultures, some people are praised if they do not show that they are suffering from a psychological problem so there is less data available from these regions so there is a cultural bias.
Evaluation of culture bias?
1) research has found evidence for cultural relativism. Afro-Caribbean people have little immunity to the flu, and children born to mothers who has the flu during their second trimester has an 88% chance increase in developing schizophrenia. Therefore there may be cultural vulnerability which means Afro-Caribbean’s might be more at risk from developing schizophrenia than the white population.
2) Barnes found research evidence for cultural differences when diagnosing schizophrenia. The ethnic culture hypothesis predicts that ethnic minorities experience less distress if they suffer from schizophrenia because social structures exists in their culture. 184 individuals were studied from different backgrounds and found that Americans has more symptoms than other cultures because they have less supportive features in their cultures.
3) one weakness is cultural relativism. Psychologists might not be able understand a patinet’s symptoms correctly due to not fully understanding the patient’s cultural background and can lead to the misdiagnosis of schizophrenia.
What is gender bias?
Male sufferers of schizophrenia tend to show more negative symptoms than women, and also seem to suffer from more substance abuse. Males have an earlier onset (18-25 years old) of schizophrenia than females (25-35 years old).
There seems to be disagreement amongst clinicians when diagnosing schizophrenia, especially when gender is taken into account. Critics argue that the DSM displays healthy behaviour for males rather than females. Therefore the DSM can be seen as gender biased, especially when classifying schizophrenia.
Evaluation of gender bias?
1) research by Kulkarni has found supporting data to suggest that females might be less vunerable than males to schizophrenia. He found the female sex hormone estradiol can help treat schizophrenia in females, especially when paired with anti-psychotic drugs, so estradiol can be seen as a protective factor for females.
2) gender bias affects diagnosis of schizophrenia. In a study, Psychologists had to judge two patients using diagnostic criteria. When the patient was male, 56% of psychologists diagnosed schizophrenia however when the patient was female 20% of psychologists diagnosed schizophrenia, so there is a gender bias that males are more likely to be classified as schizophrenic.
3) the validity of the diagnosis of schizophrenia can be questioned, especially since females develop schizophrenia 4-10 years later than males, and there are also different types of schizophrenia that males and females are more vulnerable to, which must be taken into account when diagnosing schizophrenia.
What is symptom overlap?
The positive and negative symptoms of schizophrenia are a valid diagnosis, however some of the symptoms of schizophrenia can also be found in other disorders such as depression and bipolar disorder and this is known as symptom overlap, so shared symptoms can lead to an invalid diagnosis.
Some illnesses that have symptom overlap with schizophrenic are bipolar depression, depression and schizotypical personality disorder. The person may exhibit a symptom typical of schizophrenia eg delusions but could have another condition with the same symptom eg bipolar disorder.
Evaluation of symptom overlap?
1) to support correct diagnosis of schizophrenia in a valid way, clinicians should conduct a brain scan or EEG. This can examine the brain in detail, and especially check the grey matter in the brain, Since schizophrenic people suffer from the deterioration of grey matter. People with bipolar disorder do not have reduced grey matter so can help lead to more valid diagnosis.
2) Ketter found evidence of schizophrenia being misdiagnosed as another illness, because of symptom of overlap. This causes years of delays where schizophrenic patients do not get the correct treatment that they need and their illness gets worse. Therefore is it important that patients gets a valid diagnosis first time.
3) research evidence has also shows inter-rated reliability is actually quite low, especially when asking psychologists to agreement on diagnosing schizophrenia and not another condition. It was found that only 54% of psychologists agree on the same diagnosis, so shows how different psychologists give different diagnosis to the same patient who display the same symptoms of schizophrenia.
What is the genetics explanation of schizophrenia?
Schizophrenia is inherited through generations and transmission of genes and DNA. Schizophrenia runs in families and involves a combination of genes (polygenic). The gene NRG1 contributes to the genetics of schizophrenia. NRG1 participates in glutamatergic signalling. NRG3 is another schizophrenia susceptibility gene so if these are inherited from the parent, the individual is more likely to develop schizophrenia.
What is the dopamine hypothesis?
Schizophrenic patients tend to have excess levels of the neurotransmitter dopamine in subcortical areas of the brain which increases the firing of neurons. This is known as hyperdopaminergia. They also tend to have a greater number of D2 receptors that dopamine binds to. When drugs such as phenothiazine’s are given to patients’ that block dopamine at synapses in the brain, yhe positive symptoms of schizophrenia seem to reduce eg hallucinations but negative symptoms of schizophrenia tend to remain.