Schistosomiasis Flashcards
urinary schistosomiasis symptoms include
terminal hematuria, dysuria, frequent urination hydronephrosis, pyelonephritis, squamous cell cancer of the bladder
What causes urinary schistosomiasis?
S Haematobium
north africa, sub saharan africa and middle east
What are the symptoms of intestinal schistosomiasis and what species causes this?
S mansoni.
See diarrhea, abdominal pain and intestinal ulceration and see iron deficiency anemia
What countries do we see S mansoni?
sub saharan africa, middle east, south america, and caribbean
See intestinal schistosomiasis
What are the symptoms of hepatic schistosomiasis
hepatic schistosomiasis?
hepatosplenomegaly and periportal fibrosis and subsequent portal hypertension
What causes hepatic schistosomiasis?
s Japonicum
seen in Asia, and China, Phillippines and Japan
laboratory findings of schistosomiasis infection
eosinophilia
genitourinary schistosomiasis can have
dysuria, urinary frequency, bladder outlet obstruction and terminal hematuria.
Disease with genitourinary schistosomiasis is from
granulomatous immune reaction to the deposits of schistosomal eggs in the tissues
Diagnosis of schistosomiasis
identifying and quantifying eggs in the urine and stool and serology is better due to lighter disease burden and higher test sensitivity
treatment of schistosomiasis
praziquantel
acute onset of fevers, allergic type symptoms with urticarial lesions and angioedema with high eosinophilia with recent trip to sub Saharan Africa
acute schistosomiasis syndrome (Katayama fever)
Will have history of freshwater exposure
what is Katayama fever or acute schistosomiasis
systemic hypersensitivity reaction against schistosomal eggs and larvae which occurs about 14-28 days after infection.
What do you see on CXR during Katayama fever or acute schistosomiasis
CXR has infiltrates
Katayama fever or acute schistosomiasis treatment
self limiting in days to weeks. May get corticosteroids during acute phase followed by praziquantel to prevent long term helminth infection complications (hydronephrosis and bladder squamous cell carcinoma)
long term complications of Katayama fever or acute schistosomiasis
(hydronephrosis and bladder squamous cell carcinoma)
will you see schistosomiasis eggs or have positive serological testing in Katayama fever or acute schistosomiasis
No it can be negative. So don’t rely upon this.
unremitting high fevers and severe polyarthralgia
Chikungunya fever
non pruritic red papule that forms and ulcer with granulomatous tissue at base and red margins
cutaneous leishmaniasis
Caused by sandfly
pt has flatulence, diarrhea, lactose intolerance and malabsorption but no fever.
amebiasis