antibiotics

Question 1

daily dosed medication for MRSA coverage

Answer 1

daptomycin

Question 2

monitor these labs while on daptomycin?

Answer 2

CPK

Question 3

linezolid side effects:

Answer 3

pancytopenia and granulocytosis

Question 4

vancomycin side effects:

Answer 4

interstitial nephritis and red man syndrome

Question 5

zosyn side effects

Answer 5

thrombocytopenia

Question 6

gentamycin is used to treat

Answer 6

gram negative infections

Question 7

MRSA coverage bugs:

Answer 7

vancomycin
daptomycin
linezolid

Question 8

Treatment of MRSA pneumonia

Answer 8

vancomycin
linezolid

no daptomycin - inactivated by surfactant

Question 9

amphotericin B

Answer 9

antifungal for cryptococal meningitis

cause hypomagnesemia and hypokalemia and renal toxicity

Question 10

if patient with CF is resistant to ciprofloxacin it’s not enough to cover with levofloxacin. what to give instead?

Answer 10

give cefepime or ceftazidime due to resistance to ciprofloxacin for coverage for pseudomonas

Question 11

aztreonam can be a substitute for

Answer 11

beta lactam in penicillin allergy

Question 12

anti pseudomonals are:

Answer 12

cefepime, ceftazidime, doripenem, imipenem meropenem and pipercillin-tazobactam

fluoroquinolones - ciprofloxacin and levofloxacin

amikacin and gentamicin

fluoroquinolones plus aminoglycosides

Question 13

daptomycin is meant for

Answer 13

skin and deep tissue structure infections and good coverage against MRSA

Question 14

the one fluoroquinolone without pseudomonal activity

Answer 14

moxifloxacin

Question 15

only carbapenem without antipseudomonal activity

Answer 15

ertapenem

Question 16

good CNS penetration

Answer 16

cefepime

Question 17

why do we not like nafcillin for septic emboli to brain

Answer 17

poor CNS penetration. switch to ancef instead.

zosyn also doesn’t have as good CNS penetration as cefepime.