Schistosomiasis Flashcards
Schistosomiasis
bilharziasis
Blood Fluke
Important Schistosomiasis species
s. hematobium
s. Mansoni
s. japonicum
s. mekongi
Schistosomiasis Morphology
Egg: terminal or lateral spine
Cercaria: Forked Tail
Adult Male: shorter and stouter: gynecophoral canal
Life Cycle
Egg Transverse Tissue Passed in urine or Feces Miracidium hatches from egg and finds SNAIL Sporocyst in snail Cercaria from snail finds human
Urinary Bladder
Large intestine
Small Intestine
haematobium
mansoni
japonicum & Mekongi
Pathophysiology of Schistosomiasis
Urticaria
Fever and GI complaints
build up of granulated tissue
Eggs swept back blocking sinusoidal capillaries
Soluble egg antigen, t cell dependent granuloma
granuloma kills the eggs
Leukopenia and eosinophilia
Treatment Schistosomiasis
Praziquantel
Schistosoma haematobium
Terminal Spine
bladder adult
Bladder cancer link
Schistosoma haematobium Epidemiology
Africa Middle East
aswan Dam
boys
ah-ah-ah painful urination
Schistosoma haematobium Identification
Diagnositic: Egg
Biopsy: bladder
ELISA immunoblot : Schistosome antibody
Schistosoma Mansoni
Later Spine Egg Large intestine egg granulomas hepatosplenomegaly Hepatic neoplasm
Schistosoma Mansoni Epidemiology
Africa, Caribbean South America
Schistosoma Japonicum
small lateral spine small intestine fever egg granulomas splenomegaly liver colorectal cancer
Schistosoma Japonicum Epidemiology
Eastern Asia
Reservoirs, Humans and Wild/domestic animals
ID: Fecal Concentration
Schistosoma Mekongi
similar to japonicum small lateral knob veins small intesting hepatosplenomegaly zoonotic: DOG
