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MICRO Exam 7 > Ricketsia > Flashcards

Ricketsia Flashcards

1
Q

Ricketssia transmitted humans by

A

arthropods

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2
Q

Ricketssia Characteristic

A 
Intracellular
Arthropods hosts and vectors
Humans are accidental hosts 
**EXCEPT Ricket prowazekii**
Gram Neg
Do Not Stain Well
Slime Layer
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3
Q

Ehrlichia

A

Ehrlichiosis

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4
Q

Anaplasma

A

anaplasmoses

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5
Q

Ricketsia Mech of Action

A

Attach to host,
induced phagcytosis
escape phagosome w/ phospholipase

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6
Q

Vectors of Ricketsia

A

Ticks, Mites, Lice, fleas

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7
Q

Ricketsia Pathogenesis

A

primarily endothelial cells
Necrotizing vasculitis,
EDEMA, hypoalbumemia
Typhus nodules in the brain

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8
Q

Typhus Group (2)

A

prowazekii & typhi

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9
Q

RMSF Group

A

Ricketsii and A lot of others

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10
Q

Disease and distribution ricketsii

A

RMSF and Western Hemi

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11
Q

Disease and distribution

A

Ricketssiapox & worldwide

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12
Q

Disease and distribution

A

Epidemic Typhus Worldwide

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13
Q

Disease and distribution

A

Murine Typhus World Wide

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14
Q

Rickestia Ricketsii Epidemiology

A

Most Common
Rodent and Rabbitt reservoir
Ixodid Species Tick

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15
Q

Rickestia Ricketsi Disease

A

2-14 day incubation
fever headache photophobia
RASH- macular wrists forearms, Petechial

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16
Q

Rickestia Ricketsi Complications

A

Myocarditis, CNS dysfunction, renal, gangrene

17
Q

Ricketsia akari Epidemiology

A

House mouse, Norweigan Rat, black rat

Vector- House mouse mite

18
Q

Ricketssialpox

A

Incubation 7-10 Day
1 phase- Red papule, vesicular, dark eschar
2nd phase- 3-7 days skin lesion abrupt fever, severe headache
Rash 2-3 days

19
Q

Rickestsia prowazecki Typhus Epidemiology

A

Human Body Louse— VECTOR

No transovarial transmission

20
Q

Rickestsia prowazecki Disease

A

Incubation - 7-10 days
sudden onset
rash 4-7 days after fever and macular to petechial

21
Q

Ricketsia Prowazecki Complications

A

myocarditis, CNS dysfunction

22
Q

Rickestsia prowazecki Brill-Zinnser

A

Recurrent form

less sever, rarely fatal

23
Q

Rickestsia prowazecki Sylvatic epidemic typhus

A

Reservoid squirrel,

Vector Squirrel flea

24
Q

Rickestsia typhi

A

World Wide
Rats, mouse opposum, cat
Flea is vector
Transovarial occurs in fleas

25
Q

Rickestsia typhi Disease

A

Rash Absent

26
Q

Diagnosis Ricketsii

A

Presumptive
Confirmatory
•Serology
• PCR

27
Q

Treatment Ricketsii

A

Doxycycline

Chloramphenicol: Pregnant

28
Q

Prevention Ricketsii

A

Control Reservoirs,

No vaccine availble any longer in U.S.

29
Q

Anaplasmatacae

A

Gram neg coccobacilli
Less peptidoglycan
Infect bone marrow derived cells
Morulae looked like mulberries

30
Q

Vectors of Anaplasmatacae

A

Ticks mostly

31
Q

Ehrlichia Chaffeensis HME

A

Worlde Wide
White Tail Deer, Dogs, Coyotes,
Lone Star Tick
American Dog tick

32
Q

Ehrlichia Chaffeensis HME Disease

A

Fever headache

Rash 5 days after, maculopapular, diffuse erythema

33
Q

Ehrlichia Chaffeensis HMEComplications

A

meningoencephalitis

34
Q

Anaplasma Phagocytophilum

A

World Wide
Small and medium mammal reservoir
Blacklegged
western Blacklegged

35
Q

Anaplasma Phagocytophilum HGA Disease

A

7-14 day incubation

Rash is uncommon

36
Q

Anaplasma Phagocytophilum HGA Complications

A 
ARDS
Renal fail
Toxic like
Coagulopathy
Polyneuropathy
37
Q

Diangosis of ehrlichia and anaplasma

A

Presumptive: Signs, history, Blood test, leukocytopenia
Confirmatory: PCR whole bood * IFA gold standard

38
Q

ehrlichia and anaplasma Treatment

A

Doxycycline

39
Q

ehrlichia and anaplasma Prevention

A

No vaccines, tick vector

MICRO Exam 7 (14 decks)

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