Guinea Worms Filarial Roundworms Flashcards
Dracunculus Medinensis
Guniea Worm Dranculiasis LARGE NEMATODE Larvae ovoviviparous Larvae in bath water, expelled by female worms
Life Cycle Dracunculus
female emerges
1st stage larvae eaten by copepod
Definitive host: inadvertently consumes copepod
Infective: 3rd stage larva
Pathophysiology Dracunculus Medinensis
1 yr after, worm emerges
Sub q and skin of lower extermities
Epidemiology Dracunculus Medinensis
Endemic to areas of Africa
Ponds in desert environment
Diagnosis Dracunculus Medinensis
No relieable method
Metronidazole
Surgical removal
winding around a stick
Wuchereria Bancrofti
Bancroft Filarial Worm Wuchereriasis Bancroft Filariasis ELEPHANTITIS MICROSCOPIC
Wuchereria Bancrofti Life Cycle
Fliariform Larva, infective stage,Mosquito feeds on the person, enters the woung via mosquito wound site, Migrates to lymphatics
Wuchereria Bancrofti Pathophysiology
Inflammatory response
fever-> lymphagenitis-> Lymph Stagnation -> Elephantoid
Enlargement when channels occluded
Wuchereria Bancrofti Epidemiology
Africa, Asia Haiti Brazil
Vectors- Night Feeding Mosquitos
P blood max 10PM -2AM
Wuchereria Bancrofti Diagnostic
Microfilairia in blood
Serological card tests
PCR fairly reliable
Wuchereria Bancrofti Treatment
DOC
Diethylcarbamazine
Ivermectin
Brugia Malayi
Malayan Worm
Malayan Filiariasis
Brugia Malayi Epidemiology
Asia South pacific islands
Mosquitos are vectors
Onchocerca Volvulus
Onchocerciasis or RIVER blindness
Life Cycle: Infective Stage: Filiariform
Reside in SUBQ for 15 yrs
Microfilaria ingest by black fly in blood meal
Onchocerca Volvulus Pathophysiology
No pain in nodule Elephantiasis normal skin architecture diminishes Eye Involvement -Visual -Microfiliariae -Sclerosing Keratitis