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MICRO Exam 7 > Bacterial Zoonotic > Flashcards

Bacterial Zoonotic Flashcards

1
Q

Cause of Tularemia

A

Franciscella Tularensis

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2
Q

Franciscella Epidemiology

A

Northern Hemishpere
Summer (Ticks)
Winter (rabbitts)
Vectors: Ticks and deer flies

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3
Q

Characteristics of Tularemia

A 
Fastidious, aerobe 
COCCOBACILLUS
Facult Intracellular 
Like Macrophages
Extended life in mud and carcasses
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4
Q

Method of Transmission Tularemia

A 
Arthropod bite
Direct animal contact
Aerosol
Incontaminated Water
Undercooked meat
Small Mammal Bite
NO PERSON TO PERSON
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5
Q

Alinical of arthropod

A

Ulceroglandular

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6
Q

Inhalation

A

Pneumonic

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7
Q

INgestion of meat

A

Oropharyngeal

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8
Q

Systemic Spread

A

Typhoidal

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9
Q

Autoinoculation

A

Oculoglandular

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10
Q

Ulceroglandular Tularemia

A 
Most Common, Rarely fatal
Through Skin,
Inhibits lysosome phagosome fusion; macrophages
2-5 days painful papule
Lymphadenopathy
Abrupt Onset
Spread
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11
Q

Pneumonic Tularemia

A 
High Mortality
Inhaled, multiple necrotizing granulomas
Broncho pneumonia, Bronchitis, Tracheitis
Lobar Pneumonia
Bacteremia
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12
Q

Oropharyngeal Tularemia

A 
Bacteria Ingested
Bloodstream
Endotoxemia
Fever sore throat
splenomegaly
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13
Q

Oculoglandar

A 
Rare form
Bacteria ioculated in eye
Conjuctival sac
Photophobia
mucopurulent discharge
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14
Q

Typhoidal

A

Mortality is HIGH
Systemic bloodstream
Sepsis
Pneumonia

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15
Q

Diagnosis of Tularemia

A

Culture aspirate lymph node
Special AGAR
4x increase in IgG
Antibodies cross react w/ brucella

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16
Q

Tularemia Treatment

A

Streptomycin

Doxyclcline–> relapse

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17
Q

Tularemia Prevention

A

Avoid Reservoirs and vecotrs
process in biohazard hood
live vaccine not great but reduces severity

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18
Q

Brucellosis subtypes

A

Abortus—-cattle

Melitensis— goats and sheep

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19
Q

Brucella Characteristics

A

gra neg aerobic
facultative intracellular
Range of presentation
Cure to abscess

20
Q

Brucella Epidemiology

A

Control in animal = control in humans

Unpasteurized milk

21
Q

Brucella disease presentation

A

Patient HIstory
Ingestion or animal contact
Spread via lymphatic, multiplies macrophages, becomes systemic
UNDULATING FEVER

22
Q

Burcella Disease

A

Fever Back Pain Fatigue
Abscesses and Granulomas
Arthritis Respiratory Cardiovacular

23
Q

Burcella Diagnosis

A

Lab notification
Culture various tissues
Serological tests
MIsdiagnose as mylaria or Flu

24
Q

Burcella Characteristics

A 
Obligate aerobe,
gram neg
coccobacillus
weak Lps
no motitliy
cat, ox and urease positive
Prefers Macrophages
Survival in milk, fetuses aborted,  soil, or paper
25
Q

Burcella Treatment

A

Doxycicline w/ rifampin

6+ weeks

26
Q

Burcella Prevention

A

Immunization of animals

Avoid unpasteurized

27
Q

Batonella Bacilliformis

A

bartonellosis, oroya fever

28
Q

Bartonella quintana

A

trench fever, angiomatosis

29
Q

Bartonella Henselae

A

Cat Scratch

30
Q

Bartonella elizabethae

A

endocarditis

31
Q

Bartonella Characteristics

A

gram neg
aerobic bacillus
Facult intracellular of blood and RES
Motility vaires

32
Q

Bartonella Epidemiology

A

Bacilliformis— s america only
Henselae—- cat host, others are human hosted
Bite by arthropod
Bite or scratch by Cat

33
Q

Vector Bacilliformis

A

sandfly

34
Q

vector henselae

A

cat flea

35
Q

vector quintana

A

Body Louse

36
Q

Bacilliformis

A 
biphasic
Oroya fever (Acute)
Verruga (Chronic)
Sandfly
Bloodstream multipilcation
Oroya fever by removal RBC by REC\
Fever Malaise, Myalgia, Headache
ANEMIA
37
Q

Presentation of Verruga

A

Red purple skin lesions

Recurrence

38
Q

Quintana

A 
Trench Fever, 
Body Louse transmission
Multiply in RES
sever headache
abrupt presentation
5 day recurrence
39
Q

Henselae

A

Marcophages and lymphnodes
Bacteremia septicemia occur in immunocompromised
Chronic regional lymphadenopathy

40
Q

Angiomatosis

A

Quintana or Henselae

immunocompromised

41
Q

Diagnosis

A

History

serology DFA IFA

42
Q

Bartonella Treatment

A

Azithromycin
Doxycycline
Macrolides
Doxycycline

43
Q

Cat Scrach Tx

A

Azithro

44
Q

Bartonellosis

A

Doxycycline or Chloraphenicol

45
Q

Angiomatosis Tx

A

Macrolides

46
Q

Trench Fever Tx

A

Doxycycline

MICRO Exam 7 (14 decks)

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