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COMLEX Level 2CE > SBSI drills W4 (F) > Flashcards

SBSI drills W4 (F) Flashcards

Missing M-Th drills

1
Q

what is tamsulosin used for?

A

-BPH

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2
Q

what is terazosin used for?

A
  • BPH

- HTN

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3
Q

tamsulosin and terazosin drug class = ?

A

a1 antagonists

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4
Q

what are the s/e of sildenafil and vildenafil?

A
  • low BP (if used w/ nitrates)
  • priapism
  • vision color (blue tinted vision)
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5
Q

minoxedil uses =

A
  • hair growth

- HTN

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6
Q

pulsatile leuprolide use =

A

infertility

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7
Q

constant leuprolide uses =

A
  • precocious puberty
  • fibroid
  • prostate cancer (used w/ flutamide)
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8
Q

what drug combo is used to tx prostate ca?

hint: 1 = GnRH antagonist

A
  1. leuprolide

2. flutamide

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9
Q

what does in utero exposure to DES cause?

A

clear cell ca of vagina/cervix

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10
Q

what is clomiphene used for?

A

infertility in PCOS

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11
Q

what are the s/e of tamoxifen?

A
  • DVT (High E –> hyper-coag state)
  • endometrial hyperplasia/Ca
  • hot flashes
  • *protects from osteoporosis
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12
Q

what is tamoxifen used for?

A

-ER+ breast Ca

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13
Q

what is raloxifen used for?

A

post-menopausal osteoporosis

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14
Q

what are the s/e of raloxifen?

A
  • DVT
  • hot flashes
  • NO ENDOMETRIAL EFFECTS/RISKS
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15
Q

what are the uses of mifepristone?

A
  • abortion

- high BG in pts w/ cushing dz AND DM2

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16
Q

danazol s/e = ?

A
  • wt gain
  • edema
  • acne
  • hirtuism
  • pseudotumor cerebri
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17
Q

what are the uses of danazol?

A
  • endometriosis
  • adenomyosis
  • fibroids
  • hereditary angioedema
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18
Q

what are the uses of finasteride?

A
  • BPH

- hair growth

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19
Q

what are the s/e of spironolactone?

A
  • gynecomastia

- amenorrhea

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20
Q

What are the s/e of testosterone?

A
  • balding
  • gynecomastia
  • roid rage
  • small, firm testes
  • acne
  • premature closure of growth plates
  • decr HDL, incr LDL
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21
Q

what are the s/e of oxytocin?

A
  • uterine atony
  • lactation
  • low Na
  • HTN
  • HA/seizure/vision changes
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22
Q

Mg s/e = ?

A
  • (first to manifest) hyporeflexia –> arreflexia
  • n/v
  • low Ca
  • resp depression
  • cardiac arrest (arrhythmias)
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23
Q

you see a cluster of grapes on pelvic U/S. dx = ?

A

hyatidiform mole (complete)

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24
Q

what are the karyotypes of complete hyatidiform moles?

A

46 XY

46 XX

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25
Q

which molar pregnancy presents w/ fetal parts on pelvic U/S?

A

partial mole

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26
Q

pregnant pt presents w/ painful vaginal bleeding. dx = ?

A

placental abruption

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27
Q

pregnant pt presents w/ painless vaginal bleeding. dx = ?

A
  • placenta previa

- vasa previa

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28
Q

what must you do prior to vaginal exam if pregnant pt presents w/ vaginal bleeding?

A

transABDOMINAL U/S

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29
Q

what are some (x4) ABX that have teratogenic affects?

A
  • tetracyclines
  • fluoroquinolones
  • aminoglycosides
  • sulfonamides
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30
Q

what teratogenic effect do tetracyclines have?

A

tooth discoloration/malformation

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31
Q

what teratogenic effect do fluoroquinolones have?

A

tendon rupture

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32
Q

what teratogenic effect do aminoglycosides have?

A

ototoxicity

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33
Q

what teratogenic effect do sulfonamides have?

A

neural tube defects

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34
Q

what is the MCC of post-partum hemorrhage?

A

uterine atony

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35
Q

how do you tx post-partum hemorrhage 2/2 uterine atony?

A
  1. uterine massage
  2. tocolytics
  3. uterine artery ablation
  4. hysterectomy
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36
Q

what meds are used for GBS ppx?

A
  • penicillin

- ampicillin

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37
Q

new mother fails to lactate. her delivery was complicated by post-partum hemorrhage. dx = ?

A

sheehans (pituitary necosis 2/2 hemorrhage)

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38
Q

pt presents w/ uterine bleeding @ 18 wks gestation. no fetal materials have been expulsed. the OS is open. dx = ?

A

inevitable abortion

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39
Q

pt presents w/ uterine bleeding @ 18 wks gestation. no fetal materials have been expulsed. the OS is closed. dx = ?

A

-threatened abortion

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40
Q

pt presents w/ amenorrhea, nL prolactin, no withdrawal bleeding on progestin challenge and h/o D&C. dx = ?

A

asherman’s synd

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41
Q

what drug is used to induce ovulation?

A

clomiphene

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42
Q

how do you tx PCOS?

A
  1. weight loss
  2. OCPs
  3. metformin (if insulin resistance)
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43
Q

what is the best initial test for post-menopausal uterine bleeding?

A

U/S (look for endometrial stripe thickening)

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44
Q

post-menopausal bleeder + thickened endometrial stripe on U/S. what test do you do?

A

-endometrial bx

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45
Q

how do you medically tx endometriosis?

A
  1. OCPs
  2. GnRH agonists (leuprolide)
  3. danazol
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46
Q

MC location of ectopic pregnancy implantation?

A

ampulla

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47
Q

how do you dx leiomyoma (fibroids)?

A
  • bimanual exam (enlarged, nodular, asymmetric uterus)

- U/S (fibroid visualization)

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48
Q

what do leiomyomas do w/ incr age?

A

shrink

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49
Q

pt presents w/ incr vaginal discharge + petechial patches on vagina/cervix (i.e. strawberry cervix). dx = ?

A

trichomonas cervicitis

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50
Q

kid presents w/ F for > 5 d. dx = ?

A

kawasaki dz

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51
Q

bacterial vaginosis tx = ?

A

metronidazole

52
Q

what is the MCC of bloody nipple discharge?

A

intraductal papilloma

53
Q

PID + RUQ pain. dx = ?

A

Fitz-hugh curtis

54
Q

itchy/burning erosions on nipple. dx = ?

A

paget’s dz of the breast

55
Q

what marker is elevated in ovarian ca?

56
Q

what will FSH levels be in post-menopausal women?

57
Q

what is the MCC of infertility?

A

endometriosis

58
Q

what is the NS if 2 PAP smears are ASCUS +?

A

colposcopy

59
Q

what is the tx for delerium tremens?

60
Q

how do you tx acetominophen OD?

A

n-actetyl cystein

61
Q

how do you tx opiod OD?

62
Q

how do you tx benzo OD?

A

flumazanil

63
Q

what drug can be used to tx both malig hyperthermia and NEMS?

A

dantroline

64
Q

what are the tx for malignant HTN?

A
  • nitroprusside
  • fenoldopam
  • hydralazine
  • clevidipine
  • nicardipine
65
Q

pt presents w/ macrocytic anemia + neurological s/s. dx = ?

A

vit B12 deficiency

66
Q

what antibody is associated w/ drug-induced lupus?

A

anti-histone

67
Q

burn pt presents w/ cherry red flushing and nL SaO2. dx = ?

A

CO poisoning

68
Q

how do you tx CO poisoning?

A
  • 100% O2

- hyperbaric chamber

69
Q

pt presents w/ blood in the urethral meatus or high riding prostate. ddx = ?

A
  • urethral injury

- bladder rupture

70
Q

pt presents w/ blood in the urethral meatus or high riding prostate. what test do you get?

A

retrograde cystogram

**must get before attempting to place catheter

71
Q

what is the MCC infx in burn pts?

A

pseudomonas

72
Q

pt presents in neurogenic shock. what will their BP and HR look like?

A
  • decr BP

- decr HR

73
Q

what is the MC type of tracheoesophageal fistula?

74
Q

what are the C/I to vaccination w/ the live-attenuated vaccines?

A
  • immunocomp

- pregnancy

75
Q

which vaccines are C/I if egg allergy?

A
  • YELLOW FEVER
  • flu
  • MMR
76
Q

when are further doses of pertussis vaccine C/I?

A

-pt developed encephalitis w/in 7d of prior dose

77
Q

what rxn is a C/I for all vaccines?

A

anaphylaxis after prior dose of vaccine

78
Q

what is a C/I to giving the rotavirus vaccine?

A

h/o intussusception

79
Q

bilious emesis w/in hours after first feed. dx = ?

A

duodenal atresia

80
Q

what is meconium ileus assoc w/?

81
Q

what is hirschsprungs assoc w/?

A

downs synd

82
Q

2 mos old presents w/ nonbilious emesis. dx = ?

A

pyloric stenosis

83
Q

boy presents w/ h/o chronic pulm infx + negative nitroblue test (test strip stayed yellow). dx = ?

A

chronic granulomatous dz

84
Q

4 mos old male presents w/ life threatening pseudomonas infx. what immunodeficiency do you suspect?

A

bruton’s agammaglobulnemia

85
Q

kid presents w/ eczema + thrombocytopenia + incr IgA. dx = ?

A

wiskott aldrich synd

86
Q

what is the MC immunodeficiency?

A

IgA deficiency

87
Q

how do you tx the acute phase of kawasaki dz?

A
  1. ASA

2. IVIG

88
Q

unilat loss of red light reflex in a kid suggests what?

A

retinoblastoma

89
Q

kids presents w/ sudden AMS + liver dysf(x) + n/v + recent ASA use. dx = ?

90
Q

what vaccines do you give at age 6mos?

A 
B DR HIP +/- influ
   HBV
   DTap
   Rotavirus
   Hib
   Inactivated polio vaccine
   PCV-13
   \+/- flu shot (if fall/winter)
91
Q

what is the likely etiology of small airway infx in the winter/spring?

A

RSV (dx = bronchiolitis)

92
Q

pt presents w/ red stool + ABD pain + bilious vomiting + abd mass. dx = ?

A

intussusception

93
Q

what congenital heart dz leads to UE HTN?

A

coarctation of the aorta

94
Q

what is the 1st line tx for acute OTM?

A

amoxicillin

95
Q

what is the MC etiology of croup infx?

A

parainfluenza

96
Q

small, homeless kid presents w/ peeling skin + potbelly. dx = ?

A

protein malnutrition (kwashiorkor)

97
Q

malnourished, skinny kid presents. dx = ?

98
Q

x-linked synd + gout + finger trauma. dx = ?

A

lesch nyhan synd

99
Q

how do you keep the PDA open?

A

prostaglandins

100
Q

how do you close a patent PDA?

A

indomethacin

101
Q

11 yo obese african american boy presents w/ sudden limp. dx = ?

102
Q

an active 13 yo M presents w/ anterior knee pain. dx =

A

osgood-schlatter dz

103
Q

2 mos old milestones?

A

smile and lift head

…for kiss @valentines/Feb/2nd mos

104
Q

4 mos old milestones?

A

Laugh and roll over

@ Easter. happy easter baby looking for eggs

105
Q

6 mos old milestones?

A

transfer objects from hand to hand

106
Q

when can most babies sit w/ help and w/o help?

A
  • w/ 4 mos

- w/o 6 mos

107
Q

9 mos old milestones?

A
  • wave, say mama/dada, play patty-cake
  • hold bottle
    (wave bye-bye to summer and play w/ mama and dada)
108
Q

12 mos old milestones?

A

separation anxiety

109
Q

18 mos old milestones?

A

“mine”

110
Q

2 year old milestones?

A
  • 2 word phrases

- 50% of words are discernable

111
Q

3 year old milestones?

A
  • can ride tricycle
  • can draw circle
  • uses 3 word phrases
  • 75% of words are discernable
112
Q

4 year old milestones?

A
  • hop

- can draw square

113
Q

5 yr old milestones?

A
  • walk backwards

- can draw triangle

114
Q

what is the s/e of doxyrubicin?

A

cardiomyopathy

115
Q

how do you tx cardiomyopathy 2/2 doxyrubicin use?

A

dexrazoxane (Fe chelator)

116
Q

what are the s/e of busulfan?

A
  • pulm fibrosis (think chemo man)
  • hyperpigmentation
  • myelosuppression
117
Q

what are the s/e of vincristine?

A
  • peripheral neuropathy

- paralytic ileus

118
Q

what are the uses for cisplatin?

A
  1. sm cell lung ca
  2. ovarian ca
  3. testicular ca
  4. bladder ca
119
Q

what are the s/e of cisplatin?

A
  • ototoxicity

- nephtotoxicity

120
Q

how do you ppx cisplatin nephrotoxicity?

A

amifostene

121
Q

what are the s/e of cyclosporin?

A
  • gingeval hyperplasia
  • hirtuism
  • nephrotoxic
  • neurotoxic
  • HTN
122
Q

(t 14:18) is assoc w/ which lymphoma?

A

follicular lymphoma

123
Q

(t 11:14) is assoc w/ which lymphoma?

A

mantle cell lymphoma

124
Q

(t 8:14) is assoc w/ which lymphoma?

A

burkitt lymphoma

125
Q

(t 9:22) is assoc w/ which leukemia?

126
Q

(t 15:17) is assoc w/ which leukemia?

A

AML - M3 sybtype

127
Q

what do you use to tx (t 15:17) subtype AML?

A

altransretinoic acid

COMLEX Level 2CE (23 decks)

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