SBSI drills W4 (F) Flashcards

Missing M-Th drills

1
Q

what is tamsulosin used for?

A

-BPH

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2
Q

what is terazosin used for?

A
  • BPH

- HTN

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3
Q

tamsulosin and terazosin drug class = ?

A

a1 antagonists

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4
Q

what are the s/e of sildenafil and vildenafil?

A
  • low BP (if used w/ nitrates)
  • priapism
  • vision color (blue tinted vision)
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5
Q

minoxedil uses =

A
  • hair growth

- HTN

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6
Q

pulsatile leuprolide use =

A

infertility

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7
Q

constant leuprolide uses =

A
  • precocious puberty
  • fibroid
  • prostate cancer (used w/ flutamide)
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8
Q

what drug combo is used to tx prostate ca?

hint: 1 = GnRH antagonist

A
  1. leuprolide

2. flutamide

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9
Q

what does in utero exposure to DES cause?

A

clear cell ca of vagina/cervix

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10
Q

what is clomiphene used for?

A

infertility in PCOS

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11
Q

what are the s/e of tamoxifen?

A
  • DVT (High E –> hyper-coag state)
  • endometrial hyperplasia/Ca
  • hot flashes
  • *protects from osteoporosis
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12
Q

what is tamoxifen used for?

A

-ER+ breast Ca

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13
Q

what is raloxifen used for?

A

post-menopausal osteoporosis

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14
Q

what are the s/e of raloxifen?

A
  • DVT
  • hot flashes
  • NO ENDOMETRIAL EFFECTS/RISKS
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15
Q

what are the uses of mifepristone?

A
  • abortion

- high BG in pts w/ cushing dz AND DM2

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16
Q

danazol s/e = ?

A
  • wt gain
  • edema
  • acne
  • hirtuism
  • pseudotumor cerebri
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17
Q

what are the uses of danazol?

A
  • endometriosis
  • adenomyosis
  • fibroids
  • hereditary angioedema
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18
Q

what are the uses of finasteride?

A
  • BPH

- hair growth

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19
Q

what are the s/e of spironolactone?

A
  • gynecomastia

- amenorrhea

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20
Q

What are the s/e of testosterone?

A
  • balding
  • gynecomastia
  • roid rage
  • small, firm testes
  • acne
  • premature closure of growth plates
  • decr HDL, incr LDL
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21
Q

what are the s/e of oxytocin?

A
  • uterine atony
  • lactation
  • low Na
  • HTN
  • HA/seizure/vision changes
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22
Q

Mg s/e = ?

A
  • (first to manifest) hyporeflexia –> arreflexia
  • n/v
  • low Ca
  • resp depression
  • cardiac arrest (arrhythmias)
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23
Q

you see a cluster of grapes on pelvic U/S. dx = ?

A

hyatidiform mole (complete)

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24
Q

what are the karyotypes of complete hyatidiform moles?

A

46 XY

46 XX

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25
which molar pregnancy presents w/ fetal parts on pelvic U/S?
partial mole
26
pregnant pt presents w/ painful vaginal bleeding. dx = ?
placental abruption
27
pregnant pt presents w/ painless vaginal bleeding. dx = ?
- placenta previa | - vasa previa
28
what must you do prior to vaginal exam if pregnant pt presents w/ vaginal bleeding?
transABDOMINAL U/S
29
what are some (x4) ABX that have teratogenic affects?
- tetracyclines - fluoroquinolones - aminoglycosides - sulfonamides
30
what teratogenic effect do tetracyclines have?
tooth discoloration/malformation
31
what teratogenic effect do fluoroquinolones have?
tendon rupture
32
what teratogenic effect do aminoglycosides have?
ototoxicity
33
what teratogenic effect do sulfonamides have?
neural tube defects
34
what is the MCC of post-partum hemorrhage?
uterine atony
35
how do you tx post-partum hemorrhage 2/2 uterine atony?
1. uterine massage 2. tocolytics 3. uterine artery ablation 4. hysterectomy
36
what meds are used for GBS ppx?
- penicillin | - ampicillin
37
new mother fails to lactate. her delivery was complicated by post-partum hemorrhage. dx = ?
sheehans (pituitary necosis 2/2 hemorrhage)
38
pt presents w/ uterine bleeding @ 18 wks gestation. no fetal materials have been expulsed. the OS is open. dx = ?
inevitable abortion
39
pt presents w/ uterine bleeding @ 18 wks gestation. no fetal materials have been expulsed. the OS is closed. dx = ?
-threatened abortion
40
pt presents w/ amenorrhea, nL prolactin, no withdrawal bleeding on progestin challenge and h/o D&C. dx = ?
asherman's synd
41
what drug is used to induce ovulation?
clomiphene
42
how do you tx PCOS?
1. weight loss 2. OCPs 3. metformin (if insulin resistance)
43
what is the best initial test for post-menopausal uterine bleeding?
U/S (look for endometrial stripe thickening)
44
post-menopausal bleeder + thickened endometrial stripe on U/S. what test do you do?
-endometrial bx
45
how do you medically tx endometriosis?
1. OCPs 2. GnRH agonists (leuprolide) 3. danazol
46
MC location of ectopic pregnancy implantation?
ampulla
47
how do you dx leiomyoma (fibroids)?
- bimanual exam (enlarged, nodular, asymmetric uterus) | - U/S (fibroid visualization)
48
what do leiomyomas do w/ incr age?
shrink
49
pt presents w/ incr vaginal discharge + petechial patches on vagina/cervix (i.e. strawberry cervix). dx = ?
trichomonas cervicitis
50
kid presents w/ F for > 5 d. dx = ?
kawasaki dz
51
bacterial vaginosis tx = ?
metronidazole
52
what is the MCC of bloody nipple discharge?
intraductal papilloma
53
PID + RUQ pain. dx = ?
Fitz-hugh curtis
54
itchy/burning erosions on nipple. dx = ?
paget's dz of the breast
55
what marker is elevated in ovarian ca?
ca-125
56
what will FSH levels be in post-menopausal women?
incr
57
what is the MCC of infertility?
endometriosis
58
what is the NS if 2 PAP smears are ASCUS +?
colposcopy
59
what is the tx for delerium tremens?
IV benzos
60
how do you tx acetominophen OD?
n-actetyl cystein
61
how do you tx opiod OD?
naloxone
62
how do you tx benzo OD?
flumazanil
63
what drug can be used to tx both malig hyperthermia and NEMS?
dantroline
64
what are the tx for malignant HTN?
- nitroprusside - fenoldopam - hydralazine - clevidipine - nicardipine
65
pt presents w/ macrocytic anemia + neurological s/s. dx = ?
vit B12 deficiency
66
what antibody is associated w/ drug-induced lupus?
anti-histone
67
burn pt presents w/ cherry red flushing and nL SaO2. dx = ?
CO poisoning
68
how do you tx CO poisoning?
- 100% O2 | - hyperbaric chamber
69
pt presents w/ blood in the urethral meatus or high riding prostate. ddx = ?
- urethral injury | - bladder rupture
70
pt presents w/ blood in the urethral meatus or high riding prostate. what test do you get?
retrograde cystogram | **must get before attempting to place catheter
71
what is the MCC infx in burn pts?
pseudomonas
72
pt presents in neurogenic shock. what will their BP and HR look like?
- decr BP | - decr HR
73
what is the MC type of tracheoesophageal fistula?
H type
74
what are the C/I to vaccination w/ the live-attenuated vaccines?
- immunocomp | - pregnancy
75
which vaccines are C/I if egg allergy?
- YELLOW FEVER - flu - MMR
76
when are further doses of pertussis vaccine C/I?
-pt developed encephalitis w/in 7d of prior dose
77
what rxn is a C/I for all vaccines?
anaphylaxis after prior dose of vaccine
78
what is a C/I to giving the rotavirus vaccine?
h/o intussusception
79
bilious emesis w/in hours after first feed. dx = ?
duodenal atresia
80
what is meconium ileus assoc w/?
CF
81
what is hirschsprungs assoc w/?
downs synd
82
2 mos old presents w/ nonbilious emesis. dx = ?
pyloric stenosis
83
boy presents w/ h/o chronic pulm infx + negative nitroblue test (test strip stayed yellow). dx = ?
chronic granulomatous dz
84
4 mos old male presents w/ life threatening pseudomonas infx. what immunodeficiency do you suspect?
bruton's agammaglobulnemia
85
kid presents w/ eczema + thrombocytopenia + incr IgA. dx = ?
wiskott aldrich synd
86
what is the MC immunodeficiency?
IgA deficiency
87
how do you tx the acute phase of kawasaki dz?
1. ASA | 2. IVIG
88
unilat loss of red light reflex in a kid suggests what?
retinoblastoma
89
kids presents w/ sudden AMS + liver dysf(x) + n/v + recent ASA use. dx = ?
Reye synd
90
what vaccines do you give at age 6mos?
``` B DR HIP +/- influ HBV DTap Rotavirus Hib Inactivated polio vaccine PCV-13 +/- flu shot (if fall/winter) ```
91
what is the likely etiology of small airway infx in the winter/spring?
RSV (dx = bronchiolitis)
92
pt presents w/ red stool + ABD pain + bilious vomiting + abd mass. dx = ?
intussusception
93
what congenital heart dz leads to UE HTN?
coarctation of the aorta
94
what is the 1st line tx for acute OTM?
amoxicillin
95
what is the MC etiology of croup infx?
parainfluenza
96
small, homeless kid presents w/ peeling skin + potbelly. dx = ?
protein malnutrition (kwashiorkor)
97
malnourished, skinny kid presents. dx = ?
marasmus
98
x-linked synd + gout + finger trauma. dx = ?
lesch nyhan synd
99
how do you keep the PDA open?
prostaglandins
100
how do you close a patent PDA?
indomethacin
101
11 yo obese african american boy presents w/ sudden limp. dx = ?
SCFE
102
an active 13 yo M presents w/ anterior knee pain. dx =
osgood-schlatter dz
103
2 mos old milestones?
smile and lift head | ...for kiss @valentines/Feb/2nd mos
104
4 mos old milestones?
Laugh and roll over | @ Easter. happy easter baby looking for eggs
105
6 mos old milestones?
transfer objects from hand to hand
106
when can most babies sit w/ help and w/o help?
- w/ 4 mos | - w/o 6 mos
107
9 mos old milestones?
- wave, say mama/dada, play patty-cake - hold bottle (wave bye-bye to summer and play w/ mama and dada)
108
12 mos old milestones?
separation anxiety
109
18 mos old milestones?
"mine"
110
2 year old milestones?
- 2 word phrases | - 50% of words are discernable
111
3 year old milestones?
- can ride tricycle - can draw circle - uses 3 word phrases - 75% of words are discernable
112
4 year old milestones?
- hop | - can draw square
113
5 yr old milestones?
- walk backwards | - can draw triangle
114
what is the s/e of doxyrubicin?
cardiomyopathy
115
how do you tx cardiomyopathy 2/2 doxyrubicin use?
dexrazoxane (Fe chelator)
116
what are the s/e of busulfan?
- pulm fibrosis (think chemo man) - hyperpigmentation - myelosuppression
117
what are the s/e of vincristine?
- peripheral neuropathy | - paralytic ileus
118
what are the uses for cisplatin?
1. sm cell lung ca 2. ovarian ca 3. testicular ca 4. bladder ca
119
what are the s/e of cisplatin?
- ototoxicity | - nephtotoxicity
120
how do you ppx cisplatin nephrotoxicity?
amifostene
121
what are the s/e of cyclosporin?
- gingeval hyperplasia - hirtuism - nephrotoxic - neurotoxic - HTN
122
(t 14:18) is assoc w/ which lymphoma?
follicular lymphoma
123
(t 11:14) is assoc w/ which lymphoma?
mantle cell lymphoma
124
(t 8:14) is assoc w/ which lymphoma?
burkitt lymphoma
125
(t 9:22) is assoc w/ which leukemia?
CML
126
(t 15:17) is assoc w/ which leukemia?
AML - M3 sybtype
127
what do you use to tx (t 15:17) subtype AML?
altransretinoic acid