SBSI drills W3 (F) Flashcards
Cardio, renal, & heme-onc Deck is full
What are the uses of nimodipine?
- HTN?
- prinzmetal angina?
- reynaud’s phenom?
- SAH (ppx vasospasm)
what are the uses of verapamil and diltiazem (i.e. non-d-hydropyridines)?
- HTN
- afib/aflutter
- angina
what are the s/e of CCB? (hint: think vasodilation)
- flushing
- edema
- constipation
- AV node block
hypoprolactinemia is a potential s/e of which CCB?
verapamil
gingival hyperplasia is a potential s/e of which CCB?
verapamil
what are the uses of hydralazine?
- severe hypertension
- HTN in pregnancy
- HTN in HF
nicardipine use?
HTN urgency/emergency
what are the uses of the dihydripyridines (except nimodipine)?
- HTN
- angina (including prinzmetal)
- reynaud’s phenom
what HTN meds are safe in pregnancy?
Hypertensive Moms Love Nifedipine Hydralazine Methyldopa Labetolol Nifedipine
hydralazine s/e = ?
- reflex tachy
- SLE-like synd
- fluid retention
- HA
- angina
how do you prevent the reflex tachy caused by hydralazine?
coadminister w/ BB
when do you use nitroprusside and fenoldepam?
HTN emergency
what is the s/e of nitroprusside?
CN poisoning
how do you tx CN poisoning?
- Na thiosulfate
- Na nitrate (–>oxidizes hemoglobin to methemoglobin)
- mech ventilation w/ 100% O2
what meds can you use to tx HTN emergency?
- CCB = clevidipine, nicardipine
- BB = labetolol
- nitroprusside
- fenoldopam
what are the s/e of statins?
incr LFTs
-myalgias –>rhabdo (esp if coadmin w/ fibrates and/or niacin)
co-administration of statins w/ what two other classes of cholesterol meds increases risk for rhabdo?
- fibrates
- niacin
what are the s/e of niacin?
- flushing
- hyperuricemia
- hyperglycemia
- itching
how do you tx the flushing caused by niacin use?
ASA
fibrates decr ___ more than any other type of cholesterol med?
TG
what are the s/e of fibrates?
- cholesterol gallstones
- incr LFTs
- rhabdomyolysis (when used w/ statins)
what is the clinical use of digoxin?
- HF
- afib
what are the s/e of digoxin?
- blurry yellow vision
- incr K
- arrhythmias
how do you tx digoxin OD?
- digibind
- Mg
- slowly normalize K
- cardiac pacer
what are the clinical uses for adenosine?
- NARROW complex arrythmias (afib, aflutter, SVT)
- pharm stess test
what drugs can be used to conduct chemical stress tests?
- dobutamine
- dipyridamol
- adenosine
- rigadenasone
what are the s/e of dipyridamol?
cardiac steal
adenosine s/e = ?
- flushing
- low BP
- chest pain
- impending doom
- bronchospasm
what are the uses of Mg?
- torsades de point
- digoxin toxicity
- eclampsia (seizures)
- hypocalcemia 2/2 low Mg
what are the s/e of BB?
- cardiovasc = decr HR, decr BP, AV block, HF
- CNS = sedation, sleep alterations
- masked hypoglycemia
- impotence
what are some C/I to BB use?
- asthma
- COPD
- cocaine users
how do you tx BB toxicity?
- glucagon
- saline
- atropine (for bradycardia)
what are the clinical uses of amiodarone?
WIDE complex tachycardias = vfib, vtach
what are the s/e of amiodarone?
- hypo/hyperthyroidism
- hepatotoxic
- pulm fibrosis
- blue/grey skin
- corneal deposits
- constipation
- cardiac = brady, heart block, HF
sotalol and ibutilide s/e = ?
torsades de pointes
quinidine s/e = ?
cinchonism (HA + tinnitis)
procainamide s/e = ?
-drug induced SLE
what meds decr mortality in systolic HF?
- ACEi
- ARB
- hydralazine
- nitrates
- BB = only metoprolol, bisprolol, and carvedilol
- K sparing diuretics
what meds decr mortality in MI?
- ASA
- BB
- ACEi
- ARB
which 2 statins are high intensity?
- risuvistatin
- atorvistatin
which statin is mod intensity?
simvistatin
which cholesterol med will incr HDL the most?
niacin
BB are which class of antiarrhythmics?
class 2
what additional s/e can metoprolol cause?
dyslipidemia
why don’t you give propranolol to pts w/ prinzmetal angina?
can make worse
which 2 BB will not cause unopposed a1-agonism if given alone for pheochromocytoma or cocaine toxicity?
nonselective BB = carvedilol and labetolol
what are the class 3 antiarrhythmics?
K channel blockers = AIDS Amiodarone Ibutilide Dofetilide Sotalol
what derm condition is described as a stuck on waxy appearance?
seborrheic keratosis
what derm condition is described as having red plaques with silver scales?
psoriasis
what derm condition presents w/ pearly papules with telangectasias?
BCC
what derm condition presents w/ honey crusted lesions?
impetigo
what derm condition presents w/ flaccid bullae and (+) nikolski sign?
pemphigus vulgaris
55 yo obese pt presents with velvety patches on back of neck and bilat axilla. what are these patches called?
acanthosis nigricans
what is acanthosis nigricans assoc w/ and what should you check when you see it?
insulin resistance. check BG
what derm condition presents w/ purple, plateaud (flat topped), pruritic papules?
lichen planus
what derm condition presents w/ epithelial inflammation in the anogenital region in post-menopausal pts especially?
lichen sclerosis
what derm condition presents w/ red, pruritic lesions in a geometric pattern after contact with an irritant?
contact dermatitis
what derm condition presents initially w/ a large lesion on the chest or back followed by development of smaller lesions in a christmas tree pattern (along skin folds)?
pitoryasis rosea
what derm condition presents w/ hypopigmented, flat (macular) lesions on the chest and back?
tinea versicolor
what premalignant derm condition can progress to SCC?
actinic keratosis
what is another name for cradle cap?
seborrheic dermatitis?
what derm condition presents as exophitic nodules on the skin that scale and ulcerate?
SCC
what is the most common skin cancer?
BCC
what is the 2nd most common skin cancer?
SCC
pt presents w/ tachycardia, severely high BP that is refractory to tx and diaphoresis. what do you suspect?
pheochromocytoma